3
项与 Gentuximab (GeneScience Pharmaceuticals) 相关的临床试验A Phase Ib Study to Investigate the Safety, Tolerability and Preliminary Antitumor Activity of Gentuximab in Combination With Almonertinib in Patients With EGFR Mutation-positive Metastatic Non-Small Cell Lung Cancer
This is a prospective, multicenter, open label study to investigate the safety and efficacy of Gentuximab plus Almonertinib in metastatic NSCLC patients with EGFR mutation-positive.
评估金妥昔单抗注射液联合甲磺酸阿美替尼治疗表皮生长因子受体基因突变的IV期非小细胞肺癌患者的安全性、耐受性和有效性的Ib期及Ib期扩展研究
主要目的：
（1）.在表皮生长因子受体（EGFR）基因突变的IV期非小细胞肺癌（NSCLC）患者中评估金妥昔单抗注射液联合甲磺酸阿美替尼多次给药的安全性和耐受性，并确定剂量限制性毒性（DLT）、最大耐受剂量（MTD）和联合用药推荐剂量。 次要目的：
（1）.评价金妥昔单抗联合甲磺酸阿美替尼EGFR基因突变的IV期NSCLC患者中多次给药的药代动力学（PK）特征。
（2）.评价金妥昔单抗联合甲磺酸阿美替尼治疗EGFR基因突变的IV期NSCLC患者的疗效。
（3）.评价金妥昔单抗联合甲磺酸阿美替尼在EGFR基因突变的IV期NSCLC患者的免疫原性。
An Multi-center, Open-label Phase Ib/II Study of Gentuximab Injection + Paclitaxel in Patients With Advanced Gastric or Gastroesophageal Junction Cancer to Evaluate Tolerability, Safety, Efficacy and Pharmacokinetics.
The objective of the study is to evaluate Tolerability, Safety, and primary Efficacy of Gentuximab Injection at different dosage in combination with Paclitaxel in Advanced Gastric or Gastroesophageal Junction Cancer patients, to ensure adequate treatment dosage for further study. Meanwhile, the study also evaluate Pharmacokinetics of Gentuximab Injection at different dosage in combination with Paclitaxel.
100 项与 Gentuximab (GeneScience Pharmaceuticals) 相关的临床结果
100 项与 Gentuximab (GeneScience Pharmaceuticals) 相关的专利（医药）
100 项与 Gentuximab (GeneScience Pharmaceuticals) 相关的药物交易
