VM-AD(VM-AD) - 在研适应症：特应性皮炎_专利_临床

概要

基本信息

药物类型

细胞疗法

别名

Cord blood-derived myeloid Supressor cell therapy

靶点-

作用方式-

作用机制

细胞替代物

治疗领域

免疫系统疾病遗传病与畸形皮肤和肌肉骨骼疾病

在研适应症

特应性皮炎

非在研适应症-

原研机构

ViGenCell, Inc.

在研机构

ViGenCell, Inc.

非在研机构-

权益机构-

最高研发阶段临床前

首次获批日期-

最高研发阶段(中国)-

特殊审评-

关联

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100 项与 VM-AD 相关的专利（医药）

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1

项与 VM-AD 相关的文献（医药）

Dementia and Geriatric Cognitive Disorders Extra

Qualitative Assessment of Instrumental Activities of Daily Living in Older Persons with Very Mild Dementia: The Kurihara Project

Article

作者: Nakatsuka, Masahiro ; Nakamura, Kei ; Meguro, Kenichi ; Kasai, Mari ; Ouchi, Yoshitaka

Background/Aims: We investigated quantitative/qualitative changes of instrumental activities of daily living (IADL) in people with a Clinical Dementia Rating (CDR) of 0.5. Methods: IADLs were evaluated in older residents: CDR of 0 (healthy) and CDR 0.5 (questionable/very mild dementia). The subjects with CDR 0.5 were divided into 2 types: the very mild Alzheimer's disease (vmAD) type and the other type including very mild subcortical vascular dementia. IADLs were evaluated quantitatively using the Lawton and the original qualitative IADL scales. Results: CDR 0.5/vmAD type subjects had impairment of only one Lawton item (Shopping) compared to CDR 0 subjects. However, the CDR 0.5/vmAD type group and the CDR 0.5/other type group showed impairment of 3 items in the qualitative assessment (Shopping, Food preparation, and Mode of transportation). Conclusion: We suggest using both quantitative/qualitative IADL scales for assessing older adults with very mild dementia.

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