RK-004(RK-004) - _专利_临床

概要

基本信息

药物类型

蛋白类药物

别名

靶点-

作用方式-

作用机制-

治疗领域-

在研适应症-

非在研适应症-

原研机构

RevolKa Ltd.

在研机构-

非在研机构

RevolKa Ltd.

Sekisui Polymatech Co., Ltd.

权益机构-

最高研发阶段未知

首次获批日期-

最高研发阶段(中国)-

特殊审评-

关联

100 项与 RK-004 相关的临床结果

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100 项与 RK-004 相关的转化医学

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100 项与 RK-004 相关的专利（医药）

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1

项与 RK-004 相关的文献（医药）

1990-11-01·Immunobiology4区 · 医学

A Monoclonal Antibody Recognizing Selectively Rat Granulocytes

4区 · 医学

Article

作者: Rita Kuhn ; Hermann Josef Gröne ; Friedhelm Steinhausen ; Hui Xu ; J. Hinrich Peters

In the present study, a murine monoclonal antibody, RK-4 (IgG1) specific for rat granulocytes and their precursors in blood and bone marrow is described. Results obtained by immunocytological and flowcytometry analysis showed this mAb to recognize selectively a surface antigen on neutrophils, eosinophils and basophils. Analysis of cryosections of various lymphatic and non-lymphatic organs demonstrates that this mouse antibody does not cross-react with any other structures. By flow cytometric analysis we found peripheral blood leukocytes to consist of about 15-20% granulocytes. RK-4 is therefore a valuable tool for studying differentiation and function of granulocytes under various conditions.

100 项与 RK-004 相关的药物交易

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