A randomized controlled, double-blind, multicenter study of Bushen Yijing formula for the treatment of primary osteoporosis with kidney essence deficiency

开始日期2023-08-08

申办/合作机构-

NCT05290558 / Active, not recruiting临床2期IIT

The Therapeutic Effects of Bu Shen Yi Jing Pill on Semen Quality in Sub Fertile Males: a Randomized Controlled Trial

This study aims to evaluate the safety and efficacy of Bu Shen Yi Jing (BSYJ) Pill , a type of traditional Chinese medicine, in improving male subfertility and semen parameters.

开始日期2022-01-07

申办/合作机构

KK Women's & Children's Hospital Pte Ltd.

100 项与补肾益精丸相关的临床结果

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100 项与补肾益精丸相关的转化医学

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100 项与补肾益精丸相关的专利（医药）

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项与补肾益精丸相关的文献（医药）

2006-06-01·Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine

[Effects of bushen yinao tablet on physiology and cerebral gene expression in senescence-accelerated mice].

Article

作者: Yang, Ting ; Wang, Jin-gang ; Zhang, Chong

OBJECTIVETo study the effects of Bushen Yin' ao Tablet (BSYNT) on physiology and cerebral gene expression in senescence-accelerated mice (SAM).METHODSThe change of cerebral tissues mRNA expression in SAM was analyzed and compared by messenger ribonucleic acids reverse transcription differential display polymerase chain reaction (mRNA DDRT-PCR) between the medicated group and the control group.RESULTSBSYNT could increase the level of hemoglobin (Hb) and amount of erythrocyte (RBC) of blood deficiency mice, improve the spatial learning and memory function and the escape response by conditional stimulus. In this study, 14 differential display bands had been discerned, and three of them had been sequenced. The sequence of the three fragments was similar to fatty acid binding protein 7, ubiquinol-cytochrome C reductase complex (7. 2 kD) and 60S ribosomal protein L21 respectively. And the homogeneity was 97% , 100% , and 99% , respectively.CONCLUSIONBSYNT has effect on the physiological changing of mice, and its effect on cerebral tissues mRNA expression maybe play an important role in anti-aging on the molecular level.

2001-09-01·Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine

[Experimental study of reinforcing effect of bushen yijing capsule on bone quality of cancellous bone in ovariectomy caused rats osteoporosis model].

Article

作者: Zhang, G ; Shi, Y Y ; Zhu, T Y

OBJECTIVETo explore the influence of Bushen Yijing Capsule (BSYJC) on bone quality of cancellous bone in ovariectomize induced osteoporosis rats model.METHODSForty Wistar female rats, 10 months old, were randomly divided into 4 groups, the normal group, the model control group, the premarin treated and the BSYJC treated group, 10 in each group. The normal group was only sham operated and the other three were ovariectomy performed and treated starting at day 91 postoperationally for consecutively 90 days. Rats were sacrificed at the end of experiment, the second lumbar vertebra was taken out to determine bone density and contents of calcium, phosphorus and organic substances, and the third lumbar vertebra taken out to measure the bone density and biomechanics properties. Bone quality was evaluated with the above indices.RESULTSBSYJC could significantly raise the bone density, increase the contents of calcium, phosphorus and organic substances, and improve the biomechanical properties of the lumbovertebral bone in osteoporosis rats.CONCLUSIONBSYJC could improve the bone quality of the cancellous bone in ovariectomized rats.

100 项与补肾益精丸相关的药物交易

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