Psoriasis therapeutics (Foamix)(Psoriasis therapeutics (Foamix)) - 药物靶点：CASP family_专利_临床

概要

基本信息

药物类型

未知

别名-

靶点

CASP family

作用机制

caspase调节剂(半胱天冬酶家族调节剂)

治疗领域

免疫系统疾病皮肤和肌肉骨骼疾病

在研适应症-

非在研适应症

银屑病

原研机构

VIB Corp.

在研机构-

非在研机构

VIB Corp.

VYNE Pharmaceuticals Ltd.

最高研发阶段终止药物发现

首次获批日期-

最高研发阶段(中国)-

特殊审评-

关联

100 项与 Psoriasis therapeutics (Foamix) 相关的临床结果

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100 项与 Psoriasis therapeutics (Foamix) 相关的转化医学

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100 项与 Psoriasis therapeutics (Foamix) 相关的专利（医药）

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1

项与 Psoriasis therapeutics (Foamix) 相关的文献（医药）

2020-06-01·Dermatology and Therapy4区 · 医学

Novel Coronavirus Disease (COVID-19) and Biologic Therapy in Psoriasis: Infection Risk and Patient Counseling in Uncertain Times

4区 · 医学

ArticleOA

作者: Bhutani, Tina ; Thibodeaux, Quinn G ; Reddy, Vidhatha D ; Liao, Wilson ; Chan, Stephanie Y ; Brownstone, Nicholas D ; Myers, Bridget A

With the emergence of the novel coronavirus disease (COVID-19) viral pandemic, there is uncertainty whether biologic agents for psoriasis may place patients at a higher risk for infection or more severe disease course. This commentary offers patient counseling recommendations based on the current available evidence. While there are currently no specific data for psoriasis biologics and COVID-19, data are presented here from phase III clinical trials of psoriasis biologics on rates of upper respiratory infection, influenza, and serious infection. Overall these data reveal that on the whole, psoriasis biologics do not show major increases in infection risk compared to placebo during the course of these trials. However, as the COVID-19 virus is a novel pathogen that is associated with mortality in a subset of patients, a cautious approach is warranted. We discuss factors that may alter the benefit-risk ratio of biologic use during this time of COVID-19 outbreak. Ultimately, treatment decisions should be made on the basis of dialogue between patient and provider, considering each patient's individualized situation. Once this pandemic has passed, it is only a matter of time before a new viral disease reignites the same issues discussed here.

100 项与 Psoriasis therapeutics (Foamix) 相关的药物交易

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