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作者: Goodall, Iain ; Gyan, Patrick ; Kodjo Amengor, Cedric Dzidzor ; Agboyibor, Yvonne Dogbeda ; Biniyam, Prince Danan ; Adu-Adjei, Kwabena ; Boateng, Joshua ; Ampomah-Wireko, Maxwell ; Quansah, Paul ; Zhang, En ; Adzah, Benedicta Yayra ; Osei, Michael ; Oyeh, Ernest ; Faustina, Vuvor ; Amengor, Cyril Makafui ; Ohene-Adu, Victoria ; Elmes, Victoria
An integrated computational and experimental approach validated five (5) sulphamethoxazole derivatives targeting dihydropteroate synthase (DHPS) protein as dual inhibitors of quorum sensing (LasR) and efflux pumps (AcrB) with SMX033 as the best hit.