Plainsboro, NJ, US and Bagsværd, Denmark, 27 May 2026
– Novo Nordisk today announced that new data from its cardiometabolic portfolio and pipeline will be showcased at the upcoming 2026 Scientific Sessions of the American Diabetes Association
®
(ADA), taking place in New Orleans, June 5–8, 2026. Phase 3 REIMAGINE 1–3 results evaluating the effects of investigational CagriSema on glycemic control and weight loss across a range of type 2 diabetes background therapies will be featured in an ADA Scientific Session.
1
A total of 40 abstracts will be presented, including phase 2 data assessing the safety and efficacy of investigational once-weekly injectable zenagamtide, as well as new data for Ozempic
®
and Wegovy
®
, building on the growing body of clinical evidence for semaglutide across multiple cardiometabolic conditions.
2
“The ADA’s 2026 Scientific Sessions underscores the breadth and strength of our approach to cardiometabolic diseases. From amylin-based pipeline candidates to continued expansion of our portfolio, we are building on the established and unique profile of semaglutide,” said Martin Holst Lange, executive vice president of Research & Development and chief scientific officer at Novo Nordisk. “As pioneers in this space, we remain focused on advancing innovation that can meaningfully improve the lives of millions living with serious chronic diseases.”
On Sunday, 7 June 2026, Novo Nordisk will host an R&D investor event on the science and abstracts presented at the conference. The event will be accessible via a live webcast on the
Novo Nordisk investor website
.
Select Novo Nordisk abstracts to be presented at The ADA’s 2026 Scientific Sessions, 5-8 June, New Orleans: Data for investigational uses of semaglutide and investigational medicines containing CagriSema, zenagamtide, IcoSema, and efruxifermin.
Symposium:
• REIMAGINE 1, 2, 3: Leveraging Amylin and GLP-1 for Type 2 Diabetes Care with CagriSema –
Sunday, 7 June; 4:30–6:00 pm CDT
Novo Nordisk poster and oral presentations:
CagriSema
Zenagamtide
Wegovy
®
(semaglutide injection and tablets)
Ozempic
®
(semaglutide injection and tablets)
Semaglutide for MASH
Insulin Icodec
• 1750-P Glucodynamics and Hypoglycemia Risk During Exercise or Fasting in Individuals with T2D Receiving Once-Weekly Basal Insulin Icodec
– Saturday, 6 June; 12:30–1:30 pm CDT
IcoSema
Efruxifermin
• 1294-OR Efruxifermin Improved Liver Disease and Insulin Sensitivity in Participants with Type 2 Diabetes and Metabolic Dysfunction-Associated Steatohepatitis (MASH) Cirrhosis in the SYMMETRY Trial
– Monday, 8 June; 2:45–3:00 pm CDT
Cross-product
• 1696-P Effect of Semaglutide on COVID-19-Related Complications and All-Cause Death: Pooled Analyses of the SELECT, FLOW, and SOUL Trials
– Sunday, 7 June; 12:30–1:30 pm CDT
Non-product
9 additional abstracts being presented at ADA will cover data related to cardiometabolic diseases, including type 2 diabetes, obesity, kidney, and liver disease.
CagriSema, zenagamtide, IcoSema, and efruxifermin are not approved in the United States. Safety and efficacy are not established, and there is no guarantee that these investigational medicines will become commercially available for the uses under clinical investigation.
About semaglutide
Semaglutide is a GLP-1 receptor agonist (GLP-1 RA) that is structurally similar to the naturally occurring hormone GLP-1. It works by selectively binding to and activating the GLP-1 receptor. Semaglutide has been tested in several robust clinical development programs and outcome studies in cardiometabolic diseases, including type 2 diabetes, obesity, cardiovascular disease, heart failure, chronic kidney disease, liver disease, and other related cardiometabolic diseases.
Semaglutide is marketed under the brand names Wegovy
®
(semaglutide) injection 2.4 mg, Wegovy
®
HD (semaglutide) injection 7.2 mg, Wegovy
®
(semaglutide) tablets 25 mg, Ozempic
®
(semaglutide) injection 0.5 mg, 1 mg, or 2 mg, and Ozempic
®
(semaglutide) tablets 4 mg or 9 mg.
About CagriSema
CagriSema is being investigated by Novo Nordisk as a once-weekly subcutaneous injectable treatment for adults with overweight or obesity (REDEFINE program) and as a treatment for adults with type 2 diabetes (REIMAGINE program). CagriSema is a fixed-dose combination of a long-acting amylin analog, cagrilintide and a GLP-1 receptor agonist, semaglutide.
1
About zenagamtide
Zenagamtide, formerly known as amycretin, is a unimolecular long-acting GLP-1 and amylin receptor agonist under development by Novo Nordisk, to provide a treatment for adults with overweight or obesity and as a treatment for adults with type 2 diabetes. Zenagamtide is under investigation for oral and subcutaneous administration.
About type 2 diabetes
Type 2 diabetes is a chronic condition that affects how the body processes blood sugar (glucose) for energy.
3
According to 2023 CDC data, in the United States, 40.1 million people have diabetes, with type 2 diabetes representing 90% to 95%, or an estimated 36 – 38 million people living with type 2 diabetes, making it the most common form of the disease.
3,4
About obesity
Obesity is a serious, chronic, progressive, and complex disease that requires long-term management.
5-7
One key misunderstanding is that this is a disease of just lack of willpower, when in fact there is underlying biology that may impede people with obesity from losing weight and keeping it off.
5,7
Obesity is influenced by a variety of factors, including genetics, social determinants of health, and the environment.
8,9
About Novo Nordisk
Novo Nordisk is a leading global healthcare company with a heritage of more than 100 years in diabetes care. Building on this foundation, our purpose is to drive change to defeat serious chronic diseases — from diabetes and obesity to rare blood and endocrine disorders — by pioneering scientific breakthroughs, expanding access to medicines, and working to prevent and ultimately cure disease. We are committed to long-term, responsible business practices that deliver financial, social and environmental value. Headquartered in Denmark and operating in around 80 countries, Novo Nordisk employs approximately 67,900 people and markets products in roughly 170 countries. In the United States, Novo Nordisk has a 40-year presence, is headquartered in New Jersey and employs approximately 10,000 people across more than 10 manufacturing, R&D, and corporate locations in seven states plus Washington, D.C. For more information, visit novonordisk.com and novonordiskus.com, and follow us on Facebook, Instagram, X, LinkedIn and YouTube.
Contacts for further information:
References
© 2026 Novo Nordisk All rights reserved. US26SEMO01000 May 2026