Anti-PSMA Designer T Cells(Roger Williams Medical Center)(Anti-PSMA Designer T Cells(Roger Williams Medical Center))

概要

基本信息

药物类型

CAR-T

别名-

靶点

PSMA

作用方式

抑制剂

作用机制

PSMA抑制剂(前列腺癌特异性膜抗原抑制剂)、免疫细胞毒性、T淋巴细胞替代物

治疗领域

肿瘤泌尿生殖系统疾病

在研适应症-

非在研适应症

晚期前列腺癌

原研机构

Roger Williams Realty Corp.

在研机构-

非在研机构

Roger Williams Realty Corp.

权益机构-

最高研发阶段暂停临床1/2期

首次获批日期-

最高研发阶段(中国)-

特殊审评-

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关联

3

项与 Anti-PSMA Designer T Cells(Roger Williams Medical Center) 相关的临床试验

NCT00673322

/ Terminated临床1期IIT

Phase II/Pilot Trial of Second Generation Designer T Cells in Colorectal Cancer

The purpose of this study is to collect data on the safety and effectiveness of 2nd generation designer T cells in patients with colorectal cancer. Designer T cells are prepared by collecting white blood cells from the participant, and then modifying these cells in the laboratory so that they recognize the tumor antigen (CEA). These modified cells are then given back into the participant so that they can attack and kill tumor cells.

开始日期2008-05-01

申办/合作机构

Roger Williams Realty Corp.

NCT00673829

/ Suspended临床1期IIT

Phase Ia/Ib Trial of 2nd Generation Anti-CEA Designer T Cells in Metastatic Breast Cancer

The purpose of this study is to collect data on the safety and effectiveness of 2nd generation designer T cells in patients with breast cancer. Designer T cells are prepared by collecting white blood cells from the participant, and then modifying these cells in the laboratory so that they recognize the tumor antigen (CEA). These modified cells are then given back to the participant so that they can attack and kill tumor cells.

开始日期2008-05-01

申办/合作机构

Roger Williams Realty Corp.

NCT00664196

/ Suspended临床1期IIT

Phase Ia/Ib Trial of Anti-PSMA Designer T Cells in Advanced Prostate Cancer After Non-Myeloablative Conditioning

This study tests the safety and tolerability of autologous anti-PSMA gene-modified T cells (designer T cells) in hormone refractory prostate cancer.

开始日期2008-04-01

申办/合作机构

Roger Williams Realty Corp.

100 项与 Anti-PSMA Designer T Cells(Roger Williams Medical Center) 相关的临床结果

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