COMPARATIVE EVALUATION OF TOPICAL APPLICATION OF ARGYREIA SPECIOSA GEL AND OCIMUM SANCTUM GEL AS AN ADJUNCT TO SCALING IN TREATMENT OF GINGIVITIS: A RANDOMISED CONTROLLED CLINICAL TRIAL. - NIL

开始日期2026-08-10

申办/合作机构-

CTRI/2025/04/084876

/ Not yet recruiting临床2期

An open label comparative clinical study to evaluate the enhanced effect of Guided imagery meditation with Tulsi (Ocimum sanctum Linn) capsule on professional students in Chittodvega w.s.r to Adjustment disorder - GIM

开始日期2025-05-05

申办/合作机构-

IRCT20250308064992N1

/ Recruiting临床3期IIT

The effect of Ocimum Basilicum leaf extract on the symptoms of Premenstrual Syndrome in the female university students

开始日期2025-04-21

申办/合作机构-

100 项与罗勒提取物相关的临床结果

登录后查看更多信息

100 项与罗勒提取物相关的转化医学

登录后查看更多信息

100 项与罗勒提取物相关的专利（医药）

登录后查看更多信息

106

项与罗勒提取物相关的文献（医药）

2026-04-01·POULTRY SCIENCE

Phytogenic modulation of broiler physiology: Effects of tulsi, moringa, mint, and thankuni on growth, meat quality, blood chemistry, and gut microbiota

Article

作者: Das, Shubash Chandra ; Roy, Bibek Chandra ; Amin, Anisur Rahman Al ; Siddique, Mahbubul Pratik ; Bari, Md Siam Ul ; Shihab, Saadiq Mahmud ; Islam, Rafiqul ; Khatun, Anguara ; Rabbi, Md Fazle ; Noorunnahar, Mst ; Begum, Maksuda

The global poultry industry faces increasing challenges due to the widespread use of antibiotic growth promoters (AGPs), which, while effective in enhancing broiler performance, have been linked to antimicrobial resistance, residual antibiotics in meat, and adverse impacts on human health. This research investigates the efficacy of tulsi, moringa, mint, and thankuni as phytogenic feed additives in broiler diets, aiming to evaluate the growth performance, meat quality traits, blood parameters, lipid profiles, and gut microbial populations. A total of five groups were studied over 35 days: a control group and four treatment groups supplemented with tulsi, mint, moringa, and thankuni at a rate of 2 g/kg of feed. Indian River Meat broilers were fed a corn-soya mash diet during two phases: the starter phase (0-21 days) and the grower phase (22-35 days). Results showed that the tulsi-fed group significantly increased average daily gain (ADG) compared to the control (P = 0.001). Meat quality traits remained unchanged across treatments. Concerning meat color, the tulsi group exhibited the highest redness (a*) value (P = 0.05), with no significant differences in lightness (L*) or yellowness (b*). All phytogenic feed additives positively influence blood profiles, notably hemoglobin (Hb) (P = 0.05), total erythrocyte count (TEC) (P = 0.003), and packed cell volume (PCV) (P = 0.002), with thankuni showing the highest values. Lipid indices significantly improved in the tulsi group, with reductions in total cholesterol (TC) (P = 0.001), creatinine (CRE), and low-density lipoprotein (LDL) (P = 0.01), along with increases in high-density lipoprotein (HDL) (P = 0.001) and total protein (TP) (P = 0.05) across all treatment groups. Additionally, caecal microbiota analysis revealed that the moringa group resulted in the lowest total viable count (TVC) and E. coli counts, along with the highest Lactobacillus population (P < 0.001). It can be concluded that phytogenic feed additives are promising alternatives to AGPs for improving broiler growth performance and health.

2025-12-16·International journal of clinical pediatric dentistry

Comparative In Vitro Evaluation of the Antimicrobial Efficacy of Tulsi, Triphala, and Aloe Vera against Streptococcus mutans Relative to Chlorhexidine

Article

作者: Rao, Arathi ; Saralaya, Vishwas ; Ullal, Sheetal ; Gautam, Priyanka ; Shenoy, Ramya ; Srikrishna, Suprabha Baranya ; Singh, Divya

Aim and background:

Long-term use of chlorhexidine as an antibacterial mouthwash has been associated with several adverse effects. 80% of the population in developing countries relies on traditional medicines and natural products to meet their primary healthcare needs. This study aimed to evaluate the antibacterial efficacy of herbal extracts and to compare their effectiveness with that of 0.2% chlorhexidine mouth rinse.

Methods:

The herbal extracts used were Ocimum sanctum (tulsi), a mixture of Emblica Officinalis, Terminalia chebula, and Terminalia belericia (triphala), and Aloe Barbadensis Miller (aloe vera). Blood agar plates were inoculated with Streptococcus mutans, and inhibition zones were measured after 24 hours of incubation at 37°C.

Results:

Chlorhexidine exhibited the highest antibacterial activity, followed by tulsi, triphala, and aloe vera. The mean inhibition zone diameters (in mm) were 22.33 ± 0.8, 11 ± 0.603, 8.6 ± 0.77, and 8 ± 0.6, respectively.Intergroup comparison revealed statistically significant differences (p = 0.00), favoring chlorhexidine over the herbal extracts. Intragroup analysis also showed significant differences (p = 0.00), with tulsi demonstrating the highest antibacterial activity among the herbal extracts, followed by triphala and aloe vera.

Conclusion:

Within the limitations of this in vitro study, all tested herbal extracts exhibited antibacterial properties against S. mutans. However, chlorhexidine showed the highest efficacy. Among the herbal extracts, tulsi demonstrated the most potent antibacterial activity, followed by triphala, while aloe vera exhibited the least effectiveness.

Clinical significance:

As the plant extracts demonstrated a notable efficacy in inhibiting the proliferation of oral bacteria, this suggests that these extracts could be formulated into an herbal antibacterial mouth rinse option suitable for individuals seeking herbal alternatives.

How to cite this article:

Singh D, Rao A, Saralaya V, et al. Comparative In Vitro Evaluation of the Antimicrobial Efficacy of Tulsi, Triphala, and Aloe Vera against Streptococcus mutans Relative to Chlorhexidine. Int J Clin Pediatr Dent 2025;18(12):1437-1442.

2025-12-01·VETERINARY RESEARCH COMMUNICATIONS

Ameliorative effects of Ocimum sanctum in Oreochromis niloticus against waterborne sub-lethal cadmium toxicity

Article

作者: Shah, Syed Zakir Hussain ; Ali, Shafaqat ; Hussain, Syed Makhdoom ; Khalid, Anam ; Alasmari, Abdulrahman ; Ghafoor, Abdul ; Saad, Muhammad Attaullah

This research aimed to explore the positive impacts of Ocimum sanctum on Oreochromis niloticus against waterborne cadmium (Cd) toxicity. Total 180 fish (18.41 ± 0.11 g/fish) were distributed into six experimental groups, with three replicates per group, across 18 experimental tanks. Cadmium chloride (CdCl₂) was used at a concentration of 3 µg/L. Six treatment groups were: the negative control group, without any supplement or Cd exposure; the positive control group, which received no supplements but exposed to Cd; third group with 10 g/kg supplementation along with Cd 3 µg/L exposure; fourth group with 20 g/kg supplementation along with Cd 3 µg/L exposure; fifth group with 30 g/kg supplementation along with Cd 3 µg/L exposure; and sixth group with 40 g/kg supplementation along with Cd 3 µg/L exposure. The trial lasted for sixty days. Results revealed that waterborne Cd exposure adversely affect the fish growth, body composition, and hematological parameters. However, incorporating O. sanctum considerably increased fish survival and reduced the harmful impacts of Cd. Notably, supplementation at a rate of 30 g/kg improved growth, enhanced carcass quality, and restored blood indices. Ultimately, the results showed that heavy metal toxicity could be successfully mitigated in O. niloticus aquaculture by adding 30 g/kg of O. sanctum as a nutritional supplement. The present findings suggest that the potent bioactive compounds like eugenol and urosolic acid, exhibit antimicrobial, antioxidant, stress-reducing immunostimulant, and hepatoprotective properties in O. sanctum which improve growth, body composition, and hematological parameters while mitigating the effects of Cd toxicity in O. niloticus.

100 项与罗勒提取物相关的药物交易

登录后查看更多信息