Anti-CD56 CAR T(The Affiliated Hospital of Xuzhou Medical University)(Anti-CD56 CAR T(The Affiliated Hospital of Xuzhou Medical University))

概要

基本信息

药物类型

CAR-T

别名-

靶点

CD56

作用机制

CD56抑制剂(神经细胞粘附分子-1抑制剂)、免疫细胞毒性、T淋巴细胞替代物

治疗领域

肿瘤免疫系统疾病血液及淋巴系统疾病+ [1]

在研适应症

结外NK-T细胞淋巴瘤

非在研适应症-

原研机构

徐州医科大学附属医院

在研机构

徐州医科大学附属医院

非在研机构-

最高研发阶段临床2期

首次获批日期-

最高研发阶段(中国)临床2期

特殊审评-

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关联

1

项与 Anti-CD56 CAR T(The Affiliated Hospital of Xuzhou Medical University) 相关的临床试验

NCT05941156 / Recruiting临床2期IIT

Single-center, Open, One-arm Clinical Study of the Safety and Efficacy of Anti-CD56-CAR T Therapy in Relapsed Refractory NK/T Cell Lymphoma /NK Cell Leukemia

To evaluate the safety and efficacy of anti-CD56-CAR T in the treatment of relapsed refractory NK/T cell lymphoma /NK cell leukemia

开始日期2023-05-01

申办/合作机构

徐州医科大学附属医院

100 项与 Anti-CD56 CAR T(The Affiliated Hospital of Xuzhou Medical University) 相关的临床结果

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100 项与 Anti-CD56 CAR T(The Affiliated Hospital of Xuzhou Medical University) 相关的转化医学

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100 项与 Anti-CD56 CAR T(The Affiliated Hospital of Xuzhou Medical University) 相关的专利（医药）

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1

项与 Anti-CD56 CAR T(The Affiliated Hospital of Xuzhou Medical University) 相关的文献（医药）

2017-08-01·Annals of Hematology

Anti-CD138 chimeric antigen receptor-modified T cell therapy for multiple myeloma with extensive extramedullary involvement

Letter

作者: Zhang, Yizhuo ; Yang, Hongliang ; Tian, Chen ; Zhu, Lei ; Cao, Zeng ; Zhang, Qing

This article describes about the anti-CD138 chimeric antigen receptor-modified T cell therapy for multiple myeloma with extensive extramedullary involvement in patients.¹⁸F-fluorodeoxyglucose positron emission tomog. (PET)-computed tomog. scanning showed increased ¹⁸F-fluorodeoxyglucose uptake in the nodule, stomach and thoracic vertebrae of a 52-yr-old man.Second-line treatment with lenalidomide was started and as expected the plasma cells in the bone marrow decreased significantly.This article concludes that Although the patient died due to lung infection, anti-CD138 CAR-T therapy may be a potential therapy in MM with extramedullary involvement.

100 项与 Anti-CD56 CAR T(The Affiliated Hospital of Xuzhou Medical University) 相关的药物交易

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