This study applied innovative approach for the fractionation of blackcurrant pomace (BCP) for its upcycling into higher value products.Considering that BCP is highly heterogenous material consisting of skins, pulp residues and seeds wet mech. pre-fractionation was applied for further separation of lipophilic compounds by supercritical CO2 extraction (SFE-CO2).Mech. pre-fractionation produced protein and fat enriched seed (BCS) and dietary fiber rich skin (BCSk) fractions.The SFE-CO2 recovered from BCSk and BCS 15.66% and 4.42% of extracts, resp., consisting mainly of polyunsaturated triacylglycerols.The content of polyphenolics and anthocyanins was remarkably higher in the defatted residues of BCSk than BCS, 38.79 vs 5.92 and 15.54 vs 1.02 mg/g, resp.The concentration of tocopherols and phytosterols were significantly higher in the BCSk extracts α-tocopherol and β-sitosterol being the major individual constituents; however, larger amounts of these bioactives were recovered from BCS due to the higher total extract yield.The SFE-CO2 residues contained higher amounts of dietary fiber and proteins compared with the whole BCP.In total, 120 volatile compounds were identified in BCP, its fractions and extracts by head space - solid phase microextraction and GC x GC-TOFMS.BCSk contained larger number of volatiles art higher concentrations than BCS, while SFE-CO2 efficiently recovered these compounds from the raw materials.Terpenes constituted a major group in BCSk, while aldehydes in BCS.The results indicated have the potential to be used for different food, pharmaceutical or cosmetic applications, improving the efficiency of the targeted use of pomace.