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更新于：2025-09-20
Lithium gamolenate
更新于：2025-09-20
概要
基本信息
药物类型 小分子化药 |
别名 Glamolec、LiGLA、Lithium-gamma linolenate + [3] |
作用方式 刺激剂 |
作用机制 Prostaglandin synthases stimulants |
在研适应症- |
非在研适应症 |
原研机构 |
在研机构- |
权益机构- |
最高研发阶段终止临床3期 |
首次获批日期- |
最高研发阶段(中国)- |
特殊审评- |
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结构/序列
分子式C18H30LiO2 |
InChIKeyPULYXVPPEOPWIV-HPFCUAHCSA-N |
CAS号122051-95-0 |
关联
1
项与 Lithium gamolenate 相关的临床试验NCT00612807
Adapting Marital Therapy in Older Adults With Depression
100 项与 Lithium gamolenate 相关的临床结果
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100 项与 Lithium gamolenate 相关的转化医学
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100 项与 Lithium gamolenate 相关的专利（医药）
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12,522
项与 Lithium gamolenate 相关的文献（医药）2025-12-31Italian Journal of Animal Science
Effects of dietary hemp co-product inclusion on laying hens performances and on egg nutritional and functional profile
作者: Skřivan, M. ; Englmaierová, M. ; Petrosillo, E. ; Lanzoni, D. ; Baldi, A. ; Skřivanová, V. ; Giromini, C. ; Marchetti, L. ; Bontempo, V. ; Rebucci, R.
Farm to Fork strategy aims to guide the agri-sector to sustainable food system.Hemp co-products are featured by an interesting nutritional and functional profile.The 9% inclusion of the hemp co-product improved the performance of laying hens and the nutritional and functional profile of eggs.
2025-12-31Italian Journal of Animal Science
Effects of dietary processed former foodstuffs on slaughter performance and meat quality in broilers
作者: Gasperi, Flavia ; Srikanthithasan, Karthika ; Barroeta Lajusticia, Ana Cristina ; Diaz Vicuna, Elena ; Dabbou, Sihem ; Altomonte, Iolanda ; Miraglia, Dino ; Profiti, Margherita ; Castrica, Marta ; Roccatello, Rosalba ; Giorgino, Andrea ; Gariglio, Marta ; Forte, Claudio ; Fiorilla, Edoardo ; Schiavone, Achille
This study assessed the effects of incorporating com. processed former foodstuffs (cFF) as substitutes for corn, soybean meal and soybean oil in broilers' diet on slaughter performance, physicochem. properties and meat sensory attributes.Two hundred and one-day-old male chicks (ROSS-308) were divided into four dietary groups with increasing levels of cFF (0, 6.25%, 12.5% and 25%) named cFF0, cFF6.25, cFF12.5 and cFF25, resp. On d 33, 25 chickens per dietary group were slaughtered for analyses.Carcase traits were similar across groups, except for a decrease in gizzard yield in cFF25 group (p < .008) Shear force, cooking loss and drip loss were unaffected by the diet.Meat pH decreased linearly in both breast and thigh muscles, and the thigh muscle yellowness index increased (p <.05).Breast crude protein (CP) decreased, while thigh CP and breast ether extract increased as the cFF inclusion level rose (p < .05).The fatty acid (FA) content of breast and thigh meat showed a linear increase in monounsaturated FA, with thigh meat also exhibiting a linear increase in saturated FA (SFA).Conversely, polyunsaturated FA (PUFA) and the PUFA to SFA ratio decreased with increasing cFF levels (p < .05) Lipid oxidation levels remained unchanged across groups.Sensory anal. revealed no differences in overall acceptability or liking among groups, although two sensory attributes (sour and hard) resulted as discriminating factors (p < .05).Overall, cFF inclusion did not affect meat quality, oxidative stability or consumer perception but altered the FA composition, suggesting the need of further investigation to assess the optimal inclusion level.
2025-11-01SEPARATION AND PURIFICATION TECHNOLOGY
Supercritical CO2 separation of lipids from mechanically pre-fractionated black currant pomace: Chemical composition, bioactivities and application perspectives
作者: Juriene, Laura ; Pukalskiene, Milda ; Poceviciene, Indre ; Baranauskiene, Renata ; Venskutonis, Petras Rimantas
This study applied innovative approach for the fractionation of blackcurrant pomace (BCP) for its upcycling into higher value products.Considering that BCP is highly heterogenous material consisting of skins, pulp residues and seeds wet mech. pre-fractionation was applied for further separation of lipophilic compounds by supercritical CO2 extraction (SFE-CO2).Mech. pre-fractionation produced protein and fat enriched seed (BCS) and dietary fiber rich skin (BCSk) fractions.The SFE-CO2 recovered from BCSk and BCS 15.66% and 4.42% of extracts, resp., consisting mainly of polyunsaturated triacylglycerols.The content of polyphenolics and anthocyanins was remarkably higher in the defatted residues of BCSk than BCS, 38.79 vs 5.92 and 15.54 vs 1.02 mg/g, resp.The concentration of tocopherols and phytosterols were significantly higher in the BCSk extracts α-tocopherol and β-sitosterol being the major individual constituents; however, larger amounts of these bioactives were recovered from BCS due to the higher total extract yield.The SFE-CO2 residues contained higher amounts of dietary fiber and proteins compared with the whole BCP.In total, 120 volatile compounds were identified in BCP, its fractions and extracts by head space - solid phase microextraction and GC x GC-TOFMS.BCSk contained larger number of volatiles art higher concentrations than BCS, while SFE-CO2 efficiently recovered these compounds from the raw materials.Terpenes constituted a major group in BCSk, while aldehydes in BCS.The results indicated have the potential to be used for different food, pharmaceutical or cosmetic applications, improving the efficiency of the targeted use of pomace.
1
项与 Lithium gamolenate 相关的新闻（医药）
100 项与 Lithium gamolenate 相关的药物交易
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研发状态
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| 适应症 | 最高研发状态 | 国家/地区 | 公司 | 日期 |
|---|---|---|---|---|
| 胰腺癌 | 临床3期 | 英国 | 2001-05-01 |
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