Inhibition of survivin by 2′-O-methyl phosphorothioate-modified steric-blocking antisense oligonucleotides
Article
作者: Rahimizadeh, Kamal ; Chen, Suxiang ; Veedu, Rakesh N ; Li, Yalin ; Zhang, Zhen
We have designed and screened seven fully 2′-O-methyl phosphorothioate-modified steric-blocking ASOs for specific inhibition of BIRC5 expression. As a result, ASO-7 was identified as the lead sequence.