冰醋酸/醋酸铝(Acetic acid, glacial/Aluminum acetate)

概要

基本信息

药物类型

小分子化药

别名

BOROFAIR、DOMEBORO

靶点-

作用机制-

治疗领域

耳鼻咽喉疾病

在研适应症-

非在研适应症

耳感染

原研机构-

在研机构-

非在研机构-

最高研发阶段撤市

首次获批日期-

最高研发阶段(中国)-

特殊审评-

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结构

分子式C6H12AlO6

InChIKeyRGUQYKWBLSHQCY-UHFFFAOYSA-N

CAS号139-12-8

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关联

100 项与冰醋酸/醋酸铝相关的临床结果

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100 项与冰醋酸/醋酸铝相关的转化医学

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100 项与冰醋酸/醋酸铝相关的专利（医药）

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1

项与冰醋酸/醋酸铝相关的文献（医药）

1985-09-01·Undersea biomedical research

In vitro efficacy of Otic Domeboro against Pseudomonas aeruginosa.

Article

作者: Dibb, W L

The in vitro activity of prophylactic ear drops (Otic Domeboro) which are widely used by saturation divers against external otitis has been assessed. Four strains of Pseudomonas aeruginosa, 1 reference strain and 3 clinical isolates from cases of external otitis were employed. Two of the clinical isolates were from saturation divers who were using Otic Domeboro. Otic Domeboro solution was bactericidal even when diluted 1:2 in serum or broth. There were no significant differences between strains. There was no measurable inoculum effect. Survival kinetic analysis showed 60% killing at 5 min and 99.9% killing at about 2 h. Otic Domeboro is an effective anti-P. aeruginosa agent. There was no evidence of increased resistance among strains isolated from divers. The rate of killing in relation to usual prophylactic recommendations suggests that frequent dripping may be more effective. The therapeutic use of Otic Domeboro in saturation diving should be evaluated to avoid unnecessary use of antibiotic drops.

100 项与冰醋酸/醋酸铝相关的药物交易

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