溃结康灌肠液(Kuijiekang Enema)

概要

基本信息

药物类型

中药

别名-

靶点-

作用方式-

作用机制-

治疗领域

免疫系统疾病消化系统疾病

在研适应症-

非在研适应症

溃疡性结肠炎

原研机构

天津天士力新资源药业有限公司

在研机构-

非在研机构

天津天士力新资源药业有限公司

权益机构-

最高研发阶段终止临床阶段不明

首次获批日期-

最高研发阶段(中国)终止

特殊审评-

关联

1

项与溃结康灌肠液相关的临床试验

CTR20132130

/ CompletedN/A

以美沙拉嗪肠溶片为阳性对照评价溃结康治疗溃疡性结肠炎有效性安全性多中心中央随机双盲双模拟平行对照试验

评价溃结康灌肠液对溃疡性结肠炎（湿热瘀阻证）的有效性及安全性。

开始日期2013-10-09

申办/合作机构

天津天士力新资源药业有限公司

100 项与溃结康灌肠液相关的临床结果

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100 项与溃结康灌肠液相关的转化医学

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100 项与溃结康灌肠液相关的专利（医药）

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1

项与溃结康灌肠液相关的文献（医药）

2007-08-01·Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials

[Preparation and examination of the vitro releasing of pH-dependent kuijiekang tablet for colon-specific delivery].

Article

作者: Li, Rui-zhen ; Chen, Fei-yuan ; Liao, Hua-wei

OBJECTIVE:

To prepare the pH-dependent kuijiekang tablet for colon-specific delivery used in treating the ulcerative colitis and to develop the in vitro release method of kuijiekang tablets.

METHODS:

The coating prescription was screened by the in vitro delivery of Puerarin and Berberine hydrochloride. The in-vitro releasing property of the preparation was examined by the method of in-vitro delivery.

RESULTS:

The preparation methods of the pH-dependent kuijiekang tablet for colon-specific delivery was obtained from the in-vitro delivery, Puerarin and Berberine hydrochloride were not detected in the simulated gastric fluid after 2 h and the quantitied of Puerarin and Berberine hydrochlo4de were less 10% in the simulated intestinal fluid after 4 h. The quantities of Puerarin and Berberine hydrochloride were 90.07% and 89.87%.

CONCLUSION:

It can be prepared and the preparation is a promising delivery system for drugs to be delivery to the colon.

100 项与溃结康灌肠液相关的药物交易

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