1区 · 生物学
ArticleOA
作者: Buynak, John D. ; Smith, Clyde A. ; Nguyen, Thu Q. ; Stewart, Nichole K. ; Chai, Weirui ; Lee, Mijoon ; Alqurafi, Maha A. ; Toth, Marta ; Vakulenko, Sergei B. ; Quan, Pojun
Carbapenem antibiotics are the drugs of choice for treatment of deadly infections caused by Gram-negative bacteria. However, their efficacy is severely compromised by the wide spread of carbapenem-hydrolyzing class D β-lactamases (CHDLs).