Dendritic cells vaccine(Dartmouth-Hitchcock Medical Center)(Dendritic cells vaccine(Dartmouth-Hitchcock Medical Center))

概要

基本信息

药物类型

治疗性疫苗、树突状细胞疫苗

别名-

靶点-

作用方式

刺激剂

作用机制

免疫刺激剂

治疗领域

肿瘤神经系统疾病其他疾病

在研适应症-

非在研适应症

多形性胶质母细胞瘤

原研机构

Dartmouth-Hitchcock Medical Center

在研机构-

非在研机构

Dartmouth-Hitchcock Medical Center

权益机构-

最高研发阶段无进展临床2期

首次获批日期-

最高研发阶段(中国)-

特殊审评-

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关联

3

项与 Dendritic cells vaccine(Dartmouth-Hitchcock Medical Center) 相关的临床试验

NCT00323115

/ Completed临床2期IIT

A Phase II Feasibility Study of Adjuvant Intra-Nodal Autologous Dendritic Cell Vaccination for Newly Diagnosed Glioblastoma Multiforme

Adult patients who have surgical resection of newly diagnosed glioblastoma multiforme will be treated with radiotherapy/chemotherapy followed by dendritic cell vaccine. Chemotherapy will be administered after three vaccinations for one year or until progression of disease.

开始日期2006-05-01

申办/合作机构

Dartmouth-Hitchcock Medical Center

NCT00085488

/ Completed临床1期IIT

En Vivo Matured Dendritic Cell Therapy in Patients With Melanoma

RATIONALE: Vaccines made from a patient's dendritic cells and tumor cells may make the body build an immune response to kill tumor cells.
PURPOSE: This phase I trial is studying the side effects and best dose of vaccine therapy in treating patients with stage III or stage IV melanoma.

开始日期2004-02-01

申办/合作机构

Dartmouth-Hitchcock Medical Center

[+1]

NCT00085436

/ Completed临床2期IIT

A Phase II Study Of Autologous Tumor/DC Vaccine (DC Vaccine) Combined With Interleukin-2 (IL-2) And Interferon-α-2a (IFNα-2a) In Patients With Metastatic Renal Cell Carcinoma (RCC)

RATIONALE: Vaccines made from a patient's dendritic cells and tumor cells may make the body build an immune response to kill tumor cells. Interleukin-2 may stimulate a person's lymphocytes to kill kidney cancer cells. Interferon alfa may interfere with the growth of cancer cells. Combining vaccine therapy with interleukin-2 and interferon alfa may kill more tumor cells.
PURPOSE: This phase II trial is studying how well giving vaccine therapy together with interleukin-2 and interferon alfa works in treating patients with metastatic renal cell carcinoma (kidney cancer).

开始日期2003-12-01

申办/合作机构

Dartmouth-Hitchcock Medical Center

[+1]

100 项与 Dendritic cells vaccine(Dartmouth-Hitchcock Medical Center) 相关的临床结果

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100 项与 Dendritic cells vaccine(Dartmouth-Hitchcock Medical Center) 相关的转化医学

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100 项与 Dendritic cells vaccine(Dartmouth-Hitchcock Medical Center) 相关的专利（医药）

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100 项与 Dendritic cells vaccine(Dartmouth-Hitchcock Medical Center) 相关的药物交易

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