Mesenchymal Stem Cells(The Cleveland Clinic)(Mesenchymal Stem Cells(The Cleveland Clinic))

概要

基本信息

药物类型

间充质干细胞疗法

别名-

靶点-

作用机制

干细胞替代物

治疗领域

免疫系统疾病消化系统疾病其他疾病

在研适应症-

非在研适应症

溃疡性结肠炎克罗恩病克罗恩病引起的肛周瘘+ [1]

原研机构

The Cleveland Clinic Foundation

在研机构-

非在研机构

The Cleveland Clinic Foundation

最高研发阶段终止临床1/2期

首次获批日期-

最高研发阶段(中国)-

特殊审评-

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关联

6

项与 Mesenchymal Stem Cells(The Cleveland Clinic) 相关的临床试验

NCT05578508 / Withdrawn临床1期IIT

A Phase I Study of Bone Marrow Derived Mesenchymal Stem Cells (MSCs) for the Treatment of Medically Refractory Pouchitis

The purpose of this study is to determine the safety and feasibility of using allogeneic bone marrow derived mesenchymal stem cells (MSCs) to treat people with medically refractory Pouchitis.

开始日期2022-04-01

申办/合作机构

The Cleveland Clinic Foundation

[+1]

NCT04073472 / Withdrawn临床1期IIT

A Phase I Study of Allogeneic Bone Marrow Derived Mesenchymal Stem Cells for the Treatment of Ileal Anal Anastomosis and Ileal Pouch Fistulas in the Setting of Crohn's Disease of the Pouch

The purpose of this study is to determine the safety and feasibility of using allogeneic bone marrow derived mesenchymal stem cells (MSCs) to treat people with an ileal pouch anal anastomosis (IPAA) who develop a fistula in the setting of Crohn's disease of the pouch.

开始日期2021-06-01

申办/合作机构

The Cleveland Clinic Foundation

NCT04791878 / Unknown status临床1期IIT

A Phase I Study of Adult Allogeneic Bone Marrow Derived Mesenchymal Stem Cells for Pediatric Perianal Fistulizing Crohn's Disease

This study plans to enroll 10 patients aged 13-17 years of age with refractory perianal fistulizing disease. Patients will be treated by direct injection to the fistula tract(s) with 75 million allogeneic bone marrow derived mesenchymal stem cells at baseline and again after 3 months if not completely healed.

开始日期2021-04-01

申办/合作机构

The Cleveland Clinic Foundation

100 项与 Mesenchymal Stem Cells(The Cleveland Clinic) 相关的临床结果

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100 项与 Mesenchymal Stem Cells(The Cleveland Clinic) 相关的转化医学

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100 项与 Mesenchymal Stem Cells(The Cleveland Clinic) 相关的专利（医药）

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100 项与 Mesenchymal Stem Cells(The Cleveland Clinic) 相关的药物交易

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研发状态

10 条进展最快的记录,

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适应症	最高研发状态	国家/地区	公司	日期
溃疡性结肠炎	临床2期	美国	The Cleveland Clinic Foundation	2022-04-01
克罗恩病	临床2期	美国	The Cleveland Clinic Foundation	2022-04-01
隐窝炎	临床2期	美国	The Cleveland Clinic Foundation	2022-04-01
克罗恩病引起的肛周瘘	临床2期	美国	The Cleveland Clinic Foundation	2020-10-28