Article
作者: Scheeren, Ferenc A. ; Esser-Kahn, Aaron ; Manna, Saikat ; Peters, Ruud J. R. W. ; Ramos Tomillero, Iván ; van der Schoot, Johan M. S. ; Fennemann, Felix L. ; van Dalen, Duco ; Wijfjes, Zacharias ; van Dalen, Floris J. ; Hagemans, Iris M. ; Figdor, Carl G. ; Classens, René ; Schouren, Kayleigh ; Turlings, Frederique ; van Dinther, Eric A. W. ; Le Gall, Camille M. ; Verdoes, Martijn
The aim of therapeutic cancer vaccines is to induce tumor-specific cellular immune responses. In this work, we evaluate molecularly defined DC targeted anti-DEC205 antibody fragment–antigen–adjuvant conjugates (AAA-conjugates) as vaccine platform.