RPR203494 a pyrimidine analogue of the p38 inhibitor RPR200765A with an improved in vitro potency
4区 · 医学
Article
作者: E.Jane Redford ; John E Souness ; Iain M McLay ; Nicola E Wilsher ; Frank Halley ; Alan J Collis ; Kenneth M Page ; Martyn L Foster ; Christopher Maslen
Following the discovery of RPR200765, a series of pyrimidine analogues have been prepared as backups. Amongst them, RPR203494 was identified with a better in vitro profile than RPR200765A.