Autoinducing peptide(University of Colorado School of Medicine)(Autoinducing peptide(University of Colorado School of Medicine)) - 药物靶点：附属基因调节蛋白A_在研适应症：皮肤和皮肤结构感染_专利_临床

概要

基本信息

药物类型

合成多肽

别名-

靶点

附属基因调节蛋白A

作用方式

抑制剂

作用机制

附属基因调节蛋白A抑制剂

治疗领域

感染皮肤和肌肉骨骼疾病

在研适应症

皮肤和皮肤结构感染

非在研适应症-

原研机构

The University of Colorado School of Medicine

在研机构

The University of Colorado School of Medicine

非在研机构-

权益机构-

最高研发阶段临床前

首次获批日期-

最高研发阶段(中国)-

特殊审评-

关联

100 项与 Autoinducing peptide(University of Colorado School of Medicine) 相关的临床结果

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100 项与 Autoinducing peptide(University of Colorado School of Medicine) 相关的转化医学

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100 项与 Autoinducing peptide(University of Colorado School of Medicine) 相关的专利（医药）

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1

项与 Autoinducing peptide(University of Colorado School of Medicine) 相关的文献（医药）

2022-06-28·mBio

The Ubiquitous Human Skin Commensal Staphylococcus hominis Protects against Opportunistic Pathogens

Article

作者: Horswill, Alexander R. ; Gallo, Richard L. ; Bunch, Zoie L. ; Williams, Michael R. ; Todd, Daniel A. ; Zaramela, Livia S. ; Shahbandi, Ali ; Lyon, Laurie M. ; Nguyen, Amber ; Severn, Morgan M. ; Cech, Nadja B. ; Zengler, Karsten

Human skin is home to a variety of commensal bacteria, including many species of coagulase-negative staphylococci (CoNS). While it is well established that the microbiota as a whole maintains skin homeostasis and excludes pathogens (i.e., colonization resistance), relatively little is known about the unique contributions of individual CoNS species to these interactions. Staphylococcus hominis is the second most frequently isolated CoNS from healthy skin, and there is emerging evidence to suggest that it may play an important role in excluding pathogens, including Staphylococcus aureus , from colonizing or infecting the skin.

100 项与 Autoinducing peptide(University of Colorado School of Medicine) 相关的药物交易

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