A Randomized, Double-blind, Placebo-controlled, Phase 1/2a, Multi-center Clinical Trial for Evaluation of Safety, Tolerability, and Efficacy of CordSTEM-DD in Patients With Chronic Low Back Pain Due to Lumbar Intervertebral Disc Degeneration
The purpose of this clinical study is to evaluate the safety, tolerability, and efficacy of CordSTEM-DD, an allogeneic umbilical cord-derived mesenchymal stem cell, as a cell-therapeutic drug in patients with chronic low back pain due to lumbar intervertebral disc degeneration.
Interaction of water with (silico)aluminophosphate zeotypes: a comparative investigation using dispersion-corrected DFT
2区 · 化学
Article
作者: Fischer, Michael
The adsorption of water in six structurally different aluminophosphates and their silicoaluminophosphate analogues is investigated using dispersion-corrected density-functional theory calculations. In addition to predicting the interaction energies, the structural changes of the materials upon water adsorption are assessed.
Chemical science1区 · 化学
Thermodynamic rules for zeolite formation from machine learning based global optimization
Machine learning based atomic simulation explores more than one million minima from global potential energy surface of SiAlPO system, and identifies thermodynamics rules on energetics, framework and composition for stable zeolite.
Dalton transactions (Cambridge, England : 2003)2区 · 化学
A highly flexible inorganic framework with amphiphilic amine assemblies as templates
An inorganic framework with 24-and-30-ring stacked channels showed extreme flexibility, with a volume change of up to 27.1% under pressure without undergoing a phase transformation.