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更新于：2025-05-07

Aluminum Chloride Hexahydrate

更新于：2025-05-07

概要

概要

基本信息

药物类型

小分子化药

别名

aluminum chloride hexahydrate、Drysol

靶点-

作用方式-

作用机制-

治疗领域

皮肤和肌肉骨骼疾病

在研适应症

多汗症

非在研适应症-

原研机构-

在研机构-

非在研机构-

权益机构-

最高研发阶段批准上市

首次获批日期-

最高研发阶段(中国)-

特殊审评-

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结构/序列

分子式AlCl3H12O6

InChIKeyJGDITNMASUZKPW-UHFFFAOYSA-K

CAS号7784-13-6

关联

项与 Aluminum Chloride Hexahydrate 相关的临床试验

IRCT20190212042683N2

/ CompletedN/AIIT

Comparison the effect of long-pulsed ND-YAG laser and aluminum chloride 20% in the treatment on axillary hyperhidrosis

开始日期2019-03-21

申办/合作机构

Shahid Beheshti University of Medical Sciences

NCT03416348

/ Completed临床1期IIT

Hyperhidrosis of the Residual Limb in Patients With Amputations: Developing a Treatment Approach, Aims 1 and Aim 2

The objective is to establish an evidence base for a hyperhidrosis treatment algorithm in amputees. This project will address a problem that has troubled Service members, Veterans, and civilians with amputations for decades, impacting satisfaction with prosthetic use, residual limb skin health, and negatively affecting quality of life. Prior research in this area has been limited and insufficient. The Investigators are confident that improving the evaluation and treatment of residual limb hyperhidrosis will reduce the secondary health consequences of amputation and will lead to improved quality of life. This will be accomplish by completing the following specific aims.
Aim 1: Test the validity of the Minor iodine-starch test in amputees. Hypothesis: The iodine-starch test is a valid diagnostic tool of hyperhidrosis and can be useful for the identification of focal areas of sweating on a residual limb Aim 2: Test the effectiveness of a prescription strength topical antiperspirant (Aluminum Chloride 20%) on hyperhidrosis of the residual limb.
Hypothesis: Aluminum Chloride will be more effective at controlling sweating than placebo

开始日期2018-05-08

申办/合作机构

University of Utah

[+2]

IRCT20160506027762N2

/ Completed临床3期IIT

Comparative evaluation of iontophoresis with aluminum chloride hexahydrate gel versus iontophoresis with Tap water in people with primary palmar hyperhidrosis

开始日期2018-01-21

申办/合作机构

Shahid Beheshti University of Medical Sciences

100 项与 Aluminum Chloride Hexahydrate 相关的临床结果

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100 项与 Aluminum Chloride Hexahydrate 相关的转化医学

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100 项与 Aluminum Chloride Hexahydrate 相关的专利（医药）

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1,467

项与 Aluminum Chloride Hexahydrate 相关的文献（医药）

2025-06-01·Chemical Engineering and Processing - Process Intensification

Facile preparation and characterization of α-aluminum oxide particles by ultrasonic spray pyrolysis

作者: Phan, Hoa ; Nguyen, Van Doan ; La, The Vinh

The microscopic morphol. and purity of alumina are crucial factors in determination of its practical applications in high-tech industries such as ceramics, bioceramics, catalyst carriers, and others.In the present paper, α-Al₂O₃ particles were produced by ultrasonic spray pyrolysis employing the Al(NO₃)₃·6H₂O and AlCl3·6H₂O precursors.The results of microscopic examinations, mapping investigation, and X-ray diffraction (XRD) patterns revealed that alumina formed separated hollow spherical particles with an averaging 0.8 -1.0μm in size.The sizes of the exptl. acquired alumina particles were contrasted with the theor. calculated values.The optimal parameters for alumina production such as the precursor concentration and the phase transition temperature were determined to be 1.0 M and 1223 K, resp.Fourier transform IR spectroscopy (FT-IR) confirmed that the γ- phase was converted to the α-Al₂O₃ phase.In addition, energy dispersive X-ray (EDX) and X-ray fluorescence (XRF) measurements were utilized to determine the chem. composition of the alumina powder samples, which revealed that the produced α-Al₂O₃ had purities of 99.9 and 99.8%, resp., at a sintering temperature of 1473 K.These results provide significant insights for industrial applications in the aforementioned sectors.

2025-05-01·Desalination

Ecologically friendly 2D/2D Na+-MXene/LDH for cesium adsorption in salt lakes: A comprehensive study on adsorption performance, mechanisms, and environmental impact

作者: Xiong, Chengwei ; Qiao, Lijuan ; Zhang, Peng ; Zhu, Derui ; Liu, Dahuan ; Gao, Li ; Wang, You ; Qiao, Lianlong ; Chen, Xiang ; Liu, Bingxin ; Li, Yongzhen

Cesium is a rare metal of paramount importance across various domains.Despite abundant cesium resources in Qinghai-Tibet Plateau salt lakes, concentrations remain low, and existing adsorbents generally exhibit limited adsorption capacities.Consequently, there is a pressing need for the development of an adsorbent capable of effectively separating and efficiently extracting cesium ions.This work utilizes the unique functional groups and neg. charge characteristics of the two-dimensional (2D) MXene surface to promote the precipitation and crystallization of 2D layered double hydroxides (LDH), thereby enabling the in-situ growth of hydrotalcite on the MXene surface and synthesizing a 2D/2D stacked Na⁺-MXene/LDH composite.The results indicated that Na⁺-MXene/LDH exhibited enhanced sp. surface area and interlayer spacing, introducing addnl. active sites that significantly improved Cs⁺ adsorption capacity, with a maximum recorded uptake of 961.5 mg/g, surpassing previously reported MXene-based adsorbents.Adsorption tests conducted on brines from four hydrochem. types of salt lakes on the Qinghai-Tibet Plateau revealed that Na⁺-MXene/LDH displayed the highest distribution coefficient (K^Csd) of 31.92 x 10⁴ mL/g in Dong Taijnar Lake, demonstrating a strong affinity and selectivity for Cs⁺.The mechanisms underlying the enhanced adsorption performance were elucidated.Addnl., ecol. safety assessments, along with evaluations of microbial diversity and water quality in Qinghai Lake, confirmed that Na⁺-MXene/LDH preserved microbial diversity and stabilized community structures, thereby underscoring its non-toxic and environmentally friendly characteristics.This research provides a promising adsorbent for cesium extraction from brine, with potential applications in water purification and ecol. restoration.

2025-04-01·Chemical Engineering Journal

Two isostructural aluminum-based metal − organic frameworks with multiple polar sites for reversible NH3 capture

作者: Zhu, Zhenliang ; Huang, Yaoqi ; He, Ge ; Yuan, Shaojun ; Zhang, Min

Efficient ammonia (NH₃) capture is essential for both human health and environmental protection.Porous adsorbents play a crucial role in the NH₃ removal from polluted air, as reversible phys. adsorption eliminates the need for solvents or water, thereby minimizing waste generation.The structural tunability and diversity of metal-organic frameworks (MOFs) make them promising candidates for NH₃ uptake, yet developing stable and efficient MOFs for NH₃ adsorption remains a big challenge.In this study, we developed two isostructural Al-MOFs, hydroxyl-functionalized CAU-1 (CAU-1-OH) and amino-functionalized CAU-1 (CAU-1-NH₂), which featured specific polar sites and optimal porosity for efficient NH₃ removal from air.At 25° and 1 bar, CAU-1-OH and CAU-1-NH₂ achieved NH₃ uptakes of 16.3 and 16.5 mmol g^-1, resp.Theor. calculations reveal that the hydroxyl group in CAU-1-OH, the amino group in CAU-1-NH₂, and the dense electroneg. μ₂-O group in both frameworks serve as high-d. NH₃ binding sites, playing a critical role in NH₃ capture.Dynamic breakthrough experiments demonstrate the regeneration stability and excellent separation performance of these materials, highlighting their potential for cost-effective industrial applications in low-concentration NH₃ removal from air.

100 项与 Aluminum Chloride Hexahydrate 相关的药物交易

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