碘西他酸(Iocetamic Acid) - _专利_临床

概要

基本信息

药物类型

小分子化药

别名

Iocetamic acid (USAN)、Cholebrine

靶点-

作用机制-

治疗领域

其他疾病

在研适应症-

非在研适应症

造影剂

原研机构

Mallinckrodt Plc

在研机构-

非在研机构

Mallinckrodt Medical, Inc.

最高研发阶段撤市

首次获批日期

美国 (1973-05-16),

造影剂

最高研发阶段(中国)-

特殊审评-

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结构

分子式C12H13I3N2O3

InChIKeyGSVQIUGOUKJHRC-UHFFFAOYSA-N

CAS号16034-77-8

关联

100 项与碘西他酸相关的临床结果

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100 项与碘西他酸相关的转化医学

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100 项与碘西他酸相关的专利（医药）

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26

项与碘西他酸相关的文献（医药）

1987-08-01·Die Pharmazie4区 · 医学

[Improvement of the solubility of problem drugs. 15. Alteration of iomeglamic acid-methylcellulose (MH 300)-PEG 6000 coprecipitates].

4区 · 医学

Article

作者: Fahr, F ; Fries, G ; Pollandt, P ; Kala, H ; Hückel, T

1985-10-01·Die Pharmazie4区 · 医学

Beiträge zur Verbesserung des Auflösungsverhaltens von Problemarzneistoffen. 7. Mitteilung: Iomeglamsäure-Mannitol-Schmelzerstarrungsprodukte.

4区 · 医学

Article

作者: Fahr, F ; Pollandt, P ; Zessin, G ; Kala, H

1983-05-01·American Journal of Hematology1区 · 医学

Severe thrombocytopenia following oral cholecystography with iocetamic acid

1区 · 医学

Article

作者: Carmen L. G. Insausti ; Fuad Lechin ; Bertha van der Dijs

AbstractWe report the first case of severe thrombocytopenia occurring after ingestion of a widely used cholecystographic medium, iocetamic acid. The patient had not been given any treatment before he received the gallbladder contrast medium. Onset of symptoms was acute, and the clinical course was benign with complete recovery after one week. Bone marrow aspiration showed increased numbers of megakaryocytes, suggesting that platelets were rapidly removed from circulation. In vitro tests for antiplatelet antibodies were not performed because iocetamic acid is insoluble in aqueous solutions. Since only a few cases of thrombocytopenia following ingestion of iodine‐compounds have been reported, it seems highly unlikely that purpura will be, in the future, a major hazard in cholecystography. However, it would be wise to question patients as to any prior sensitivity to iodine before proceeding with oral cholecystography.

100 项与碘西他酸相关的药物交易

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