TML-2(TML-2) - _专利_临床

概要

基本信息

药物类型

蛋白类药物

别名

靶点-

作用方式-

作用机制-

治疗领域

肿瘤

在研适应症-

非在研适应症

肿瘤

原研机构

香港中文大学

在研机构-

非在研机构-

权益机构-

最高研发阶段无进展临床前

首次获批日期-

最高研发阶段(中国)-

特殊审评-

关联

100 项与 TML-2 相关的临床结果

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100 项与 TML-2 相关的转化医学

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100 项与 TML-2 相关的专利（医药）

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1

项与 TML-2 相关的文献（医药）

1996-03-01·Immunopharmacology

The immunomodulatory and antitumor activities of lectins from the mushroom Tricholoma mongolicum

Article

作者: H.X. Wang ; T.B. Ng ; W.K. Liu ; S.T. Chang ; V.E.C. Ooi

TML-1 and TML-2 were two lectins isolated from the mushroom Tricholoma mongolicum. They did not differ appreciably in their pH stability and cationic requirement for hemagglutinating activity. They both stimulated the production of nitrite ions and activated the macrophages in mice. The two lectins were able to inhibit the growth of implanted sarcoma 180 cells by 68.84% and 92.39% respectively. The growth of tumor cells in the mouse peritoneal cavity was also inhibited by the two lectins with TML-2 expressing a greater potency.

100 项与 TML-2 相关的药物交易

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