Retroviral SF71-gp91phox transduced CD34+ cells(Hospital of the Johann Wolfgang Goethe University)(Retroviral SF71-gp91phox transduced CD34+ cells(Hospital of the Johann Wolfgang Goethe University))

概要

基本信息

药物类型

基因疗法、细胞疗法

别名-

靶点-

作用方式-

作用机制

Gene transference(基因转移)

治疗领域

免疫系统疾病遗传病与畸形血液及淋巴系统疾病+ [1]

在研适应症-

非在研适应症

慢性肉芽肿病

原研机构

Hospital of the Johann Wolfgang Goethe University

在研机构-

非在研机构

Johann Wolfgang Goethe-Universität Frankfurt am MainHospital of the Johann Wolfgang Goethe University

权益机构-

最高研发阶段无进展临床1/2期

首次获批日期-

最高研发阶段(中国)-

特殊审评-

登录后查看时间轴

关联

2

项与 Retroviral SF71-gp91phox transduced CD34+ cells(Hospital of the Johann Wolfgang Goethe University) 相关的临床试验

NCT00927134

/ Completed临床1/2期IIT

Phase I/II Gene Therapy Study for X-linked Chronic Granulomatous Disease in Children

The aim of the study is to evaluate the side effects and risks after infusion of retroviral gene corrected autologous CD34+ cells of the peripheral blood of chemotherapy conditioned (busulphan) children with chronic granulomatous disease (CGD). Also gene corrected and functional active granulocytes in the peripheral blood and the engraftment in the bone marrow of the patients will be monitored an documented.

开始日期2004-06-01

申办/合作机构

University of Zurich

[+1]

NCT00564759

/ Unknown status临床1/2期IIT

Phase I/II Gene Therapy Study for X-Linked Chronic Granulomatous Disease

The aim of the study is to evaluate the side effects and risks after infusion of retroviral gene corrected autologous CD34+ cells of the peripheral blood of chemotherapy conditioned (busulphan)patients with chronic granulomatous disease (CGD). Also gene corrected and functional active granulocytes in the peripheral blood and the engraftment in the bone marrow of the patients will be monitored an documented.

开始日期2004-01-01

申办/合作机构

Hospital of the Johann Wolfgang Goethe University

[+1]

100 项与 Retroviral SF71-gp91phox transduced CD34+ cells(Hospital of the Johann Wolfgang Goethe University) 相关的临床结果

登录后查看更多信息

100 项与 Retroviral SF71-gp91phox transduced CD34+ cells(Hospital of the Johann Wolfgang Goethe University) 相关的转化医学

登录后查看更多信息

100 项与 Retroviral SF71-gp91phox transduced CD34+ cells(Hospital of the Johann Wolfgang Goethe University) 相关的专利（医药）

登录后查看更多信息

100 项与 Retroviral SF71-gp91phox transduced CD34+ cells(Hospital of the Johann Wolfgang Goethe University) 相关的药物交易

登录后查看更多信息