Bacillus Anthracis Vaccine (Syntiron)(Bacillus Anthracis Vaccine (Syntiron))

概要

基本信息

药物类型

预防性疫苗

别名-

靶点-

作用机制-

治疗领域

感染

在研适应症-

非在研适应症

炭疽

原研机构

Syntiron LLC

在研机构-

非在研机构

Syntiron LLC

最高研发阶段终止临床前

首次获批日期-

最高研发阶段(中国)-

特殊审评-

关联

100 项与 Bacillus Anthracis Vaccine (Syntiron) 相关的临床结果

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100 项与 Bacillus Anthracis Vaccine (Syntiron) 相关的转化医学

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100 项与 Bacillus Anthracis Vaccine (Syntiron) 相关的专利（医药）

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1

项与 Bacillus Anthracis Vaccine (Syntiron) 相关的文献（医药）

2007-01-01·In Vitro Transcription and Translation Protocols

In Vitro Screen of Bioinformatically Selected Bacillus anthracis Vaccine Candidates by Coupled Transcription, Translation, and Immunoprecipitation Analysis

Review

作者: Gat, Orit ; Grosfeld, Haim ; Shafferman, Avigdor

The availability of the Bacillus anthracis genome sequence allowed for in silico selection of a few hundred open reading frames (ORFs) as putative vaccine candidates. To screen such a vast number of candidate ORFs, without resorting to laborious cloning and protein purification procedures, methods were developed for generation of PCR elements, compatible with in vitro transcription-translation and immunoprecipitation, as well as with their evaluation as DNA vaccines. Protocols will be provided for application of these methods to analyze the anti-B. anthracis antibody repertoire of hyperimmune sera or sera from convalescent and from DNA-vaccinated animals.

100 项与 Bacillus Anthracis Vaccine (Syntiron) 相关的药物交易

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