A review. Watson Inc. has been manufacturing water-soluble films for more than 40 years. Mr. John Watson, a water-soluble film pioneer, envisioned supplying his added value ingredients to his bakery customers in a novel delivery system called Sol-U-Paks. Sol-U-Paks were designed from a cold water-soluble polymer, hydroxypropylmethylcellulose (HPMC), and were intended to be used as a unit-dose delivery system. This ensured that the consumer would be able to consistently add the ingredient to a batch with accuracy, and the batching operator would not be exposed to the added value ingredients. Using a vertical form, fill, and seal machine, the cold water-soluble Sol-U-Paks would be filled at Watson Inc. with the customer's ingredient. Next, the company would ship the package to the customer, and the batching operator could then immediately add the Sol-U-Pak to the batch. In the past 5 years or so, the US consumer has come to accept these water-soluble films as a novel delivery system called Quick-Dissolve Strips. Quick-Dissolve Strips are a convenient way to deliver active pharmaceutical ingredients (APIs) to the consumer because they are easier to swallow, as the filmstrip dissolves in the oral cavity before ingestion. No water is needed for the filmstrips to dissolve, so this is an added convenience for the consumer. Water would be needed if the API were to be delivered using the traditional tablet/capsule delivery system. Quick-Dissolve Strips are also an improvement over elixirs, which are messy and difficult to dispense with accuracy. The primary focus of this article is to review some of the phys. attributes needed to design a Quick-Dissolve Strip to ensure consumer acceptance. A secondary discussion will focus on a different water-soluble film, which is intended to deliver the API vaginally. Finally, taste-masking and mouth-feel techniques used to design caffeine and benzocaine Quick-Dissolve Strips will be discussed.