Performance of microcrystalline cellulose of different types from adjuvants was compared. Particle size, whiteness, mobility, bulk d., tap d. were determined, prescription was designed and its characteristics in tablets was observed MCC-CG was suitable for wet granulation; MCC-101 was suitable for adhesives, especially for wet granulation; MCC-102 had good mobility and was suitable for direct compression. Microcrystalline cellulose of different types was targeted to solve the problem of prescription tablets.