The various features that can enhance the management of the operation of reverse osmosis (RO) systems are discussed with the purpose to assist operations personnel in the design, specification, and implementation of RO monitoring software. These features can strengthen the capabilities of the operations personnel to improve RO performance, solve problems, and reduce system operation and membrane replacement costs. Three different manual data entry software options, i.e., spreadsheet software, membrane manufacturer's software, custom-designed RO software, and their useful features are discussed.