Case studies are presented that show how computer control involving parallel synthesis in specially designed reactors, particularly on the 25-100 mL scale, can provide significant benefits to the development cycle of new synthetic compounds of com. interest.The application of computer control to a variety of processes is discussed, particularly the combination of automation with statistical design packages for process optimization.By employing a combination of calorimetry data and other anal. measurements, small-scale experimentation can produce data that is both representative and scaleable.
