study's risk-benefit ratio is acceptable, there is still the potential for research participants to be harmed during the course of the study For instance, participants could be harmed as a result of unintended research consequences or research misconduct.3 Continuing ethics review is one method REBs can use to ensure that the rights and well-being of research participants are protected throughout the course of a research study. REBs can conduct continuing ethics review through either a passive or active process.4 Passive continuing review encompasses the review of a study report completed by researchers about the study's status. The material in a study report varies but typically includes information on study enrollment, serious adverse events, protocol violations, and other study problems. Active continuing review is more varied and can include formal review of the informed consent process, monitoring by a safety-monitoring committee, periodic review of documents
