更新于:2024-11-01

CDT1

基本信息

别名
CDT1、chromatin licensing and DNA replication factor 1、DNA replication factor Cdt1
+ [3]
简介
Required for both DNA replication and mitosis (PubMed:11125146, PubMed:22581055, PubMed:21856198, PubMed:14993212, PubMed:26842564). DNA replication licensing factor, required for pre-replication complex assembly. Cooperates with CDC6 and the origin recognition complex (ORC) during G1 phase of the cell cycle to promote the loading of the mini-chromosome maintenance (MCM) complex onto DNA to generate pre-replication complexes (pre-RC)(PubMed:14672932). Required also for mitosis by promoting stable kinetochore-microtubule attachments (PubMed:22581055). Potential oncogene (By similarity).

分析

对领域进行一次全面的分析。
对领域进行一次全面的分析。
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