更新于:2024-04-01

NARS1

asparaginyl-tRNA synthetase 1

基本信息

别名
AsnRS、Asparagine--tRNA ligase, cytoplasmic、Asparaginyl-tRNA synthetase
+ [4]
简介
Catalyzes the attachment of asparagine to tRNA(Asn) in a two-step reaction: asparagine is first activated by ATP to form Asn-AMP and then transferred to the acceptor end of tRNA(Asn) (PubMed:9421509, PubMed:32738225, PubMed:32788587). In addition to its essential role in protein synthesis, acts as a signaling molecule that induced migration of CCR3-expressing cells (PubMed:30171954, PubMed:12235211). Has an essential role in the development of the cerebral cortex, being required for proper proliferation of radial glial cells (PubMed:32788587).

分析

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对领域进行一次全面的分析。
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