Rectovaginal Fistula

Rising cases of psoriasis globally are fueling the need for next-gen treatment option for the disease The market is estimated to gain sizable sales avenues in North America due to presence of favorable reimbursement policies ALBANY, N.Y., June 24, 2022 /PRNewswire/ -- The psoriasis treatment market outlook by Transparency Market Research (TMR) expects the global market to expand at a CAGR of 8.7% during the forecast period, 2022-2031. The study provides exhaustive analysis of factors impacting the market growth including ongoing trends of the psoriasis treatment market. This aside, it sheds light on the psoriasis treatment market statistics, which include revenues, sales, volume, and shares of the market. Among different drug class, players in the psoriasis treatment market are expected to observe continue growth in the demand for interleukin inhibitors during the forecast period. This growth is ascribed to factors such as advanced safety and effectiveness of drugs in this class for the psoriasis treatment. Increase in the adoption of this drug class is attributed to interleukin blockers, which are known as an effective option for individuals whose body doesn't show response to other treatment solutions, notes a TMR analysis on the global psoriasis treatment market. Request Brochure of Psoriasis Treatment Market Research Report – Psoriasis Treatment Market: Key Findings The popularity of biologics is being increasing in the recent years owing to their ability to help in the treatment of psoriasis with moderate to severe levels, note analysts of a TMR study on the global psoriasis treatment market. Biologics are being increasingly adopted as they help in controlling the symptoms and providing improved skin clearance and quality of life to psoriasis patients. Hence, global market study on psoriasis treatment notes that the adoption of biologics is estimated to increase in the near future. Thus, the psoriasis treatment market revenue analysis by TMR expects the market to grow from US$ 18.8 Bn in 2021 and reach a valuation of more than US$ 44 Bn by 2031. The demand for personalized medicines is being increasing in the recent years owing to the ability of this technique to offer promising patient outcomes. Considering this fact, companies operating in the global psoriasis treatment market are focusing on the development of biosimilars and next-gen modalities. Hence, they are seen investing heavily in R&Ds. This aside, the market players are increasing efforts to gain approval for next-gen biologic drugs intended for the treatment of psoriasis. Moreover, several leading companies are executing the strategies of acquisitions and collaborations in order to maintain their prominent positions in the global psoriasis treatment market. Request for Analysis of COVID-19 Impact on Psoriasis Treatment Market – Psoriasis Treatment Market: Growth Boosters Surge in the prevalence of psoriasis across the globe is bolstering the global market Increase in the availability of next-gen treatment solution intended for psoriasis in emerging economies is propelling the psoriasis treatment market Rise in the new product launches is likely to drive the market in the near future Get Exclusive PDF Sample Copy of Psoriasis Treatment Market Report – Psoriasis Treatment Market: Regional Analysis The psoriasis treatment market in North America is expected to maintain its dominating positon during the forecast period owing to many factors such as the presence of favorable reimbursement policies and rising cases of psoriasis in the region The Asia Pacific psoriasis treatment market is anticipated to expand at rapid pace during the forecast period owing to many factors including rise in understanding on psoriasis and available treatment solutions in several developing nations of the region Make an Enquiry Before Buying – Psoriasis Treatment Market: Key Players Some of the key players profiled in the report are: Eli Lilly and Company Amgen, Inc. Merck & Co., Inc. Novartis AG Pfizer, Inc. Johnson & Johnson AbbVie, Inc. AstraZeneca plc Biogen, Inc. LEO Pharma A/S Psoriasis Treatment Market Segmentation Drug Class TNF Inhibitors Interleukin Inhibitors Vitamin D Analogs Corticosteroids Others Route of Administration Oral Parenteral Topical Distribution Channel Hospital Pharmacies Retail Pharmacies Others Regions Covered North America Latin America Europe Latin America Middle East & Africa Modernization of healthcare in terms of both infrastructure and services have pushed the healthcare industry to new heights, Stay Updated with Latest Healthcare Industry Research Reports by Transparency Market Research: TNF Inhibitors Market: The rise in global occurrence of autoimmune illnesses such as Psoriasis, Inflammatory Bowel Disorder, Rheumatoid Arthritis (RA), and Crohn's disease, as well as the rise in the elderly populace, are the primary reasons likely to drive the expansion of the global TNF inhibitors market. Vitamin D Testing Market: Rise in the prevalence of vitamin D deficiency and the surging focus on its importance contribute to the increase in screening for vitamin D serum levels, which, in turn, boosts the growth of the global vitamin D testing market. Vitamin Deficiency Treatment Market: Rise in global geriatric population and high demand for Vitamin D and Vitamin B complex due to numerous health benefits are projected to drive the global vitamin deficiency treatment market. Acute Exacerbation of CRS Treatment Market: Acute Exacerbation of CRS Treatment Market is driven by rise in mucosal inflammation incidences leading to rhinosinusitis is expected to drive the demand for acute CRS exacerbation treatment over the next few years. Amblyopia Treatment Market: Amblyopia treatment market is driven by rise in prevalence of amblyopia and launch of technologically advanced products are projected to drive the global amblyopia treatment market. Varicose Veins Treatment Market: Global varicose veins treatment market is driven by the rise in prevalence of varicose veins. Recent improvements in varicose veins treatment devices, such as compression therapy devices or ablation devices, has led to an increase in demand for these devices. Glioblastoma Multiforme Treatment (GBM) Market: The rise in prevalence of chronic diseases such as cancer, cardiovascular diseases, and diabetes is expected to drive the glioblastoma multiforme (GBM) treatment market. Recto-vaginal Fistula Treatment Market: Rise in prevalence of Crohn's disease leading to the occurrence of recto-vaginal fistula drives the global recto-vaginal fistula treatment market. About Us Transparency Market Research is a global market intelligence company providing syndicated research reports and services. Our exclusive blend of quantitative forecasting and trends analysis provides forward-looking insights for thousands of decision makers. Our experienced team of Analysts, Researchers, and Consultants use proprietary data sources and various tools & techniques to gather and analyze information. Our data repository is continuously updated and revised by a team of research experts, so that it always reflects the latest trends and information. With a broad research and analysis capability, Transparency Market Research employs rigorous primary and secondary research techniques in developing distinctive data sets and research material for business reports. For More Research Insights on Leading Industries, Visit Our YouTube Channel and hit subscribe for Future Update - Contact Us: Rohit Bhisey Transparency Market Research Inc. CORPORATE HEADQUARTER DOWNTOWN, 1000 N. West Street, Suite 1200, Wilmington, Delaware 19801 USA Tel: +1-518-618-1030 USA – Canada Toll Free: 866-552-3453 Website: Blog: Email: [email protected] Logo: SOURCE Transparency Market Research

本文首发于 博雅生命 撰文：Dr韦 近年来，间充质干细胞治疗疾病的潜力不断被证实，并逐渐得到认可。随着临床的发展，间充质干细胞在多个疾病领域形成了专家共识，或被写进疾病治疗的专家共识当中。业内专家学者共同探索了干细胞在多个疾病领域的系统化、科学化、规范化和标准化，以及安全有效应用的路径共识。 本文汇总目前可查阅到的间充质干细胞治疗疾病相关的专家共识，帮助大家了解间充质干细胞在不同疾病治疗领域的专家建议。 异体间充质干细胞治疗系统性红斑狼疮专家共识 2022年1月，《中华风湿病学杂志》发布了由国内风湿免疫学领域众多专家共同完成的《异体间充质干细胞治疗系统性红斑狼疮专家共识》。 DOI：10.3760/cma.j.cn141217-20210923-00381 多项临床研究已经证实，间充质干细胞治疗SLE患者安全有效。为了规范间充质干细胞的临床应用，专家组对间充质干细胞治疗SLE的适应证、用法、输注次数及细胞数、输注前用药及输注后合并用药以及在合 并妊娠、感染和肿瘤等情况时的应用制定了推荐意见。 这次《异体间充质干细胞治疗系统性红斑狼疮专家共识》的发布，规范了MSCs治疗SLE的基本原则、开展MSCs临床治疗的必备条件、MSCs的质量标准以及MSCs使用的来源、剂量、疗效判断等诸多细节，为未来开展相关临床试验及临床应用提供高级别证据。 共识原文：http://rs.yiigle.com/CN141217202201/1348291.htm 间充质干细胞写入中国2021“慢性GVHD”专家共识 2021年，《中华血液学杂志》发表了《慢性移植物抗宿主病（cGVHD）诊断与治疗中国专家共识（2021年版）》，此次专家共识中，针对cGVHD的预防主要有移植物来源选择、免疫抑制药物以及间充质干细胞。 （三）间充质干细胞（MSC） MSC是一群具有自我更新和多系分化的多功能细胞，独特的免疫调节作用使其在移植免疫方面有广泛应用前景。MSC防治cGVHD的机制尚待明确。研究表明，MSC可通过促进调节性T细胞（Treg细胞）增殖活化，调控Th1/Th2比例发挥免疫调节作用；也可通过上调CD27+记忆B细胞数量、降低血清B细胞激活因子（BAFF）水平和促进B细胞表面BAFF受体表达而诱导免疫耐受。研究发现，经MSC治疗的aGVHD患者后期cGVHD发生率降低。MSC输注的最佳剂量、最佳时间、最佳疗程仍需临床探索。有报道显示，在造血重建稳定后给予MSC输注（1×106/kg每月1次，共4次）可有效预防单倍型移植cGVHD的发生。 共识原文：http://rs.yiigle.com/CN121090202104/1319147.htm 间充质干细胞治疗新型冠状病毒肺炎专家共识 2021年，《传染病信息)》杂志发表了《间充质干细胞治疗新型冠状病毒肺炎专家共识》，对间充质干细胞治COVID-19提出了建议，包括了患者的选择、细胞输注的准备、细胞输注的监测和不良反应处理、疗效评价指标等。 并提出了实施要求： 基于上述共识并结合 MSC 治疗 COVID-19 的前期研究结果，为了提高 COVID-19 的救治效果、减少并发症，建议在 COVID-19 定点收治医院并按照国家有关管理办法开展 MSC 治疗。相关标准可参照《药品管理法》和国家食品药品监督管理 总局颁布的《药品注册管理办法》，或原国家卫生和计划生育委员会和原国家食品药品监督管理 总局联合制定的《干细胞临床研究管理办法（试行）》执行。 共识原文： http://www.crbxx.mil.cn/ch/reader/view_abstract.aspx?file_no=20210202&flag=1 干细胞移植规范化治疗肝硬化失代偿的专家共识 2005年，德国学者首次将干细胞用于肝病治疗，证实干细胞可以促进肝脏再生。近年来，国内外学者进行了大量干细胞移植治疗肝脏疾病的临床探索研究。 2014年，中华医学会医学工程学分会干细胞工程学组发布了我国第1个干细胞移植规范化治疗失代偿期肝硬化的专家共识。 2021年，中华医学会医学工程学分会干细胞工程专业学组颁布《干细胞移植规范化治疗肝硬化失代偿的专家共识(2021)》。 为了进一步规范化、科学化和标准化我国干细胞移植治疗失代偿期肝硬化的临床研究，中华医学会医学工程学分会干细胞工程学组组织有关专家对干细胞移植规范化治疗失代偿期肝硬化进行论证，更新共识，以期对今后的干细胞移植治疗失代偿肝硬化的临床工作提供参考和指导。 该共识囊括了干细胞移植治疗肝硬化失代偿期的临床应用规范以及干细胞移植治疗肝硬化失代偿期的研究重点。 共识原文：http://www.lcgdbzz.org/article/doi/10.3969/j.issn.1001-5256.2021.07.012 干细胞在整形修复美容领域研究和临床试验专家共识 2021年，《中国美容整形外科杂志》刊发了《干细胞在整形修复美容领域研究和临床试验的专家共识》，目的是沟通和提高我国整形修复美容领域从事干细胞基础和临床研究工作者的认知，以更好的推动干细胞的临床转化应用研究。 该共识探索干细胞在整形修复美容领域的系统化、科学化、规范化和标准化，以及安全有效应用路径的共识，已具备扎实的科学理论和实践基础。本共识邀请国内外干细胞基础研究的一线专家和整形修复美容外科领域干细胞研究的前沿临床研究专家共同撰写，达成的每项陈述和推荐均至少有 3 位相关领域的专家总结。 共识提到，在整形修复美容领域应用研究常见的干细胞类型有骨髓间充质干细胞、脂肪来源干细胞、脐带间充质干细胞、毛囊间充质干细胞、牙髓间充质干细胞、胚胎干细胞、诱导性多功能干细胞等其他干细胞。 干细胞及其衍生物的治疗是具有重要临床应用前景的再生医学手段。在整形修复美容外科领域经过了多年的基础与临床研究证明其在促进皮肤再生与修复、组织血管化、软组织再生、骨与软骨修复、多组织年轻化及毛囊再生等多方面均有较好的治疗效果。但是仍需看到干细胞应用中存在的致突变、致瘤等问题并未完全解决，尤其是治疗的标准化问题未解决，说明干细胞在治疗疾病中的作用机制、应用方法、安全性和有效性等基础和临床研究均需进一步完善。 DOI：10.3969/j.issn.1673-7040.2021.01.001 克罗恩病肛瘘诊断与治疗的专家共识意见 2018年我国《炎症性肠病诊断与治疗的共识意见 》的展望中，认为MSC移植将来也是符合成本—效益的临床治疗方案。 《中华炎性肠病杂志》2019年发表的克罗恩病肛瘘诊断与治疗的专家共识意见中则明确推荐MSC是治疗克罗恩病肛瘘的有效方法。 14.干细胞局部注射等其他治疗方法对pfCD有一定治疗作用。等级判定：推荐 干细胞局部注射对pfCD有一定的治疗作用。近期在欧洲7个国家和以色列共49家医院进行的一项多中心的三期随机、双盲、平行、安慰剂对照的临床试验（ADMIRE-CD，NCT01541579）报道了局部注射自体脂肪来源的间质干细胞对CD复杂性肛瘘的疗效。该研究共纳入212例患者，24周时治疗组和安慰剂组症状缓解率分别为49.5%和34.3%（P= 0.024），该结果表明干细胞对pfCD患者有一定的治疗作用，且目前尚未见干细胞相关不良反应的报道。视频辅助肛瘘治疗（video-assisted anal fistula treatment，VAAFT）等新手术方法尚不成熟。目前只有一篇研究报道了VAAFT在pfCD中的应用。该方法的优点是可以在64%的病例中识别出术前未发现的额外分支瘘管。适应证包括无直肠炎、直肠狭窄或并发肛周感染的经括约肌肛瘘、括约肌上肛瘘以及直肠阴道瘘（瘘管位于直肠阴道间隙下2/3）。 共识原文：http://rs.yiigle.com/resource_static.jspx?contentId=1129470 骨关节炎临床药物治疗专家共识 2021年，《中国医学前沿杂志(电子版) 》发表了《骨关节炎临床药物治疗专家共识》，在生物制剂一栏提到了间充质干细胞。 3.7.4 间充质干细胞 间充质干细胞广泛存在于各类组织中，经诱导后可分化为成骨细胞或软骨细胞，可用于修复受损的骨或软骨，在OA的治疗中已有应用，但其临床疗效和安全性尚需大量随机对照试验验证。 共识原文：http://www.yixueqianyan.cn/CN/abstract/abstract3673.shtml 结语： 间充质干细胞广泛存在于脐带、胎盘等各类组织中，具有多向分化潜能和免疫调节等功能。随着对间充质干细胞研究的深入，其在促进组织修复与再生、疾病治疗等的领域作用也得到了越来越多的关注。目前，间充质干细胞在系统性红斑狼疮、肝硬化、整形美容修复等领域的基础研究及临床试验研究逐渐形成专家共识，为其在多系统疾病领域的研究及未来临床转化提供重要的参考与支持，有助于进一步规范化间充质干细胞的临床发展。

Procedure trays are used in several hospital procedures. These trays contain different types of disposable products needed during a particular procedure. Procedure trays provides the user with various single-use components, thereby improving convenience of managing surgical interventions. The components in the procedure trays differ from procedure to procedure. Usage of these trays ensures reduced waste generation and more procedures in less time. Custom procedure trays are resourceful, as these provide health care professionals with all the sterile instruments, disposable products, and tools required for specific procedures. The use of pre-packed or custom procedure trays eliminates the requirement to stock individual components in bulk separately. Custom procedure trays or pre-packed procedure trays reduce the setup time, decrease patient wait time, and improve the overall efficiency of work and overall inventory management system. Read Report Overview - Introduction of various rules and regulations in the past to implement better facilities, inventories and certain practices led to improved and efficient procedure and several healthcare services. For instance, in 2006, the U.S. implemented the Health Act, which makes it mandatory for health care establishments to implement certain practices to prevent and control infections associated with treatments. This has made the usage of custom procedure trays and other health care related equipment imperative in medical practices. These regulations further ensure increased emphasis on measures to control infections, thereby directly promoting the use of custom procedure trays to negate the chances of any form of infection. According to National Center for Health Statistics, in 2009, the number of inpatient surgeries performed in the U.S. was estimated to be 48 million. Additionally, rise in preference for minimally invasive surgeries across the globe has triggered the growth of the procedure trays market. Every year more patients are undergoing minimally invasive surgeries owing to lower associated risks compared to conventional surgeries. However, absence of standardization at a global level is anticipated to restrain the global procedure trays market in the next few years. Request Brochure of Report - The global procedure trays market can be segmented based on product, end-user, and region. In terms of product, the market can be classified into angiography, operating room, ophthalmology, and others. Based on end-user, the global procedure trays market can be categorized into ambulatory surgical centers, hospitals, clinics, and other health care facilities. Request for Analysis of COVID-19 Impact on Procedure Trays Market- In terms of region, the global procedure trays market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America accounted for major share of the global market in terms of revenue in 2017. High growth of the market in the region can be attributed to increase in the number minimally invasive surgeries, favorable reimbursement policies by governments, and surge in health care expenditure. Europe accounted for significant share of the global procedure trays market in terms of revenue in 2017. However, the market in Asia Pacific is expected to expand at a high CAGR during the forecast period. Increase in the number of surgical procedures (both invasive and minimally invasive), rise in medical tourism, availability of experienced health care professionals, and adoption of advanced technologies & devices in the region are expected to drive the procedure trays market during the forecast period. The market in Middle East & Africa and Latin America is projected to witness moderate growth during the forecast period. This can be attributed to improving health care services, favorable governmental regulations, and rise in health care expenditures. Pre Book Medicated Chewing Gums Market Report - Key players operating in the global procedure trays market include Mölnlycke Health Care AB, Owens & Minor, Inc., Merit Medical Systems, Cardinal Health, BD, Teleflex Incorporated., B. Braun Melsungen AG, 3M, Medline Industries, Inc., and Nelipak Healthcare. More Trending Reports by Transparency Market Research: Recto-Vaginal Fistula Market Recto-vaginal fistula can be described as abnormal epithelial line connected between the rectum and vagina. Fistulas can be the outcome of acquired etiologies or congenital malformations. Recto-vaginal fistulas can also be caused due to childbirth. Active Pharmaceutical Ingredient Market Active pharmaceutical ingredient (API) refers to the active component in a drug. In simple terms, API is part of any drug that produces the intended effects. Drugs are usually formed from several components. The API acts as the primary ingredient. Aesthetic Market In the last few years, the manufacturers have created novel aesthetic gadgets, resulting in a rise in demand for aesthetic treatments. In the next few years, technologically sophisticated goods such as non-invasive body sculpting devices that employ fat freezing technology, for example, are likely to generate profitable prospects. About Us Transparency Market Research is a next-generation market intelligence provider, offering fact-based solutions to business leaders, consultants, and strategy professionals. Our reports are single-point solutions for businesses to grow, evolve, and mature. Our real-time data collection methods along with ability to track more than one million high growth niche products are aligned with your aims. The detailed and proprietary statistical models used by our analysts offer insights for making right decision in the shortest span of time. For organizations that require specific but comprehensive information we offer customized solutions through ad hoc reports. These requests are delivered with the perfect combination of right sense of fact-oriented problem solving methodologies and leveraging existing data repositories. TMR believes that unison of solutions for clients-specific problems with right methodology of research is the key to help enterprises reach right decision. 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