更新于：2024-11-01

Soft tissue contusion

软组织挫伤

更新于：2024-11-01

基本信息

别名

SOFT TISSUE CONTUSION、Soft tissue contusion、軟部組織挫傷

+ [1]

简介-

关联

项与软组织挫伤相关的药物

Traumatic Injury Ointment

跌打损伤软膏

靶点-

作用机制-

在研机构

义乌市振伟中草药科技开发有限公司 [+1]

原研机构-

在研适应症

软组织挫伤 [+1]

非在研适应症-

最高研发阶段临床2期

首次获批国家/地区-

首次获批日期1800-01-20

项与软组织挫伤相关的临床试验

ACTRN12624000721505 / Not yet recruitingN/AIIT

The effect of cannabidiol (CBD) on recovery of muscle function, muscle activation and pain following contusion injury in healthy males

开始日期2024-10-01

申办/合作机构

Massey University

NCT05853224 / RecruitingN/A

An Interventional, Pre-Market, Double-Blinded, Controlled, Two Stages Study to Evaluate the Safety and Performance of Crosslinked Hyaluronic Acid Hydrogel (With and Without Lidocaine) for the Treatment of Soft Tissue Deficits

The aim of this interventional, pre-market, double- blinded, controlled, two stages study is to evaluate the performance and safety of Crosslinked Hyaluronic Acid (CLHA) Hydrogel (with and without Lidocaine) for the Treatment of Soft Tissue Deficits.

开始日期2022-04-02

申办/合作机构-

CTR20192436 / Recruiting临床2期

跌打损伤软膏治疗软组织挫伤有效性和安全性的随机双盲、安慰剂对照、多中心Ⅱ期探索性临床试验

以“疼痛VAS评分”为主要疗效指标，采用随机、双盲单模拟、安慰剂对照、多中心临床试验设计，评价跌打损伤软膏用于治疗软组织挫伤（气滞血瘀证）的有效性和安全性的临床试验，并进行初步的剂量探索。

开始日期2020-08-27

申办/合作机构

义乌市振伟中草药科技开发有限公司

[+1]

100 项与软组织挫伤相关的临床结果

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100 项与软组织挫伤相关的转化医学

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0 项与软组织挫伤相关的专利（医药）

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1,669

项与软组织挫伤相关的文献（医药）

2024-11-01·International Journal of Surgery Case Reports

5 months old neglected anterior shoulder dislocation treated with open reduction and laterjet procedure: A case report

Article

作者: Elmi, Hassan Abdirahman ; Elmi, Hassan Sh Abdirahman ; Walhad, Hodan ; Said, Abdirahman Ibrahim ; Ali, Abdirahman Omer ; Abdulahi, Mohamoud

INTRODUCTIONShoulder dislocation is very common. However, neglected or chronic shoulder dislocations are extremely rare. The position of the humeral head determines the classification of shoulder dislocation. Anterior shoulder dislocation accounts for most cases, while inferior dislocation is rare. Negligence from the patient and misdiagnosis are the leading causes of chronic shoulder dislocation. Treatment of the condition poses a significant challenge for surgeons since there is no widely accepted treatment protocol.CASE PRESENTATIONA 56-year-old woman presented with a neglected anterior subglenoid dislocation of the shoulder joint. The dislocation occurred due to a cow kick, and initial treatment from a traditional healer and an unqualified health practitioner failed. Clinical examination and X-ray confirmed the dislocation without associated fractures. An initial attempt at closed reduction under sedation was unsuccessful. Subsequently, open reduction and a Latarjet procedure were performed successfully, resulting in a satisfactory outcome.DISCUSSIONChronic anterior dislocation primarily affects the elderly population. Open reduction and fixation procedures have shown satisfactory outcomes. The choice of treatment depends on several factors, including bone deficiencies, soft tissue damage, and the presence of Hill-Sachs or Bankart lesions. Open reduction and laterjet procedure is a validated treatment. However, early physical therapy contributes to favorable outcomes.CONCLUSIONThe condition's rarity makes it difficult to establish a well-accepted treatment protocol. Early and strict rehabilitation protocols will lead to a favorable outcome.

2024-11-01·Injury

Prosthesis applications and challenges in children with earthquake-related amputations

Article

作者: Basaran, Sibel ; Kundakci, Bugra ; Sariyildiz, Aylin ; Bicer, Omer Sunkar ; Olmez, Sila

BACKGROUNDAmputations are among the most important traumatic injuries caused by earthquakes. However, data on amputee children and prosthesis application is quite limited in the literature. The aim of the study is to evaluate the injury-related data, stump problems, prosthesis application, difficulties and complications experienced with prosthesis during follow-up of children with 2023 Kahramanmaraş earthquake-related limb loss.PATIENTS AND METHODSSociodemographic and injury-related data, pre-amputation and post-amputation interventions, prosthesis application, current prosthetic problems, and revision surgeries of the amputee children were recorded.RESULTSMedian age of patients (n = 102) admitted to our center was 13.0 years. 67.6 % of patients had one or more concomitant injuries. Median time and number of amputations were 4 (0-57) days and 1 (1-4), respectively. Of the total 120 amputations, 67.5 % (n = 81) were lower extremity amputations. Most common amputation levels were transtibial (29.1 %, n = 35), transfemoral (22.5 %, n = 27), and transhumeral (15.8 %, n = 19). Most amputees (56.8 %) underwent revision surgery after initial amputation. Median duration of time from amputation to prosthesis application was 184 (28-314) days. For 25 prostheses, a socket revision was required. Six patients had surgical revision of the stumps to allow prosthetic fit and mobility (due to bone overgrowth, soft tissue failure, heterotopic ossification).CONCLUSIONLimited healthcare facilities, surgeries performed under emergency conditions, accompanying multiple traumas, inadequate follow-up conditions, and additional difficulties arising from the pediatric patient group lead to difficulties in the care of pediatric amputee patients. Our results will guide the care of this vulnerable patient population in the event of a similar unfortunate disaster.

2024-11-01·The American Surgeon™

An Abdominal Seat Belt Sign is Associated With Similar Incidence of Hollow Viscus Injury but Increased In-Hospital Mortality in Older Adult Trauma Patients: A PCSA Multicenter Study

Article

作者: Patel, Deven ; Nahmias, Jeffry ; Sundel, Margaret ; Ghneim, Mira ; Dhillon, Navpreet K. ; Costantini, Todd W. ; Wang, Andrew ; Biffl, Walter L. ; Quintana, Megan T. ; Santorelli, Jarrett E. ; Kim, Dennis Y. ; Delaplain, Patrick T. ; Campion, Eric M. ; Keeley, Jessica A. ; Switzer, Emily ; Estroff, Jordan M. ; Sullivan, Brittany G. ; Kirby, Katharine A. ; Schellenberg, Morgan ; Robinson, Caitlin K. ; Schaffer, Kathryn B. ; Behdin, Samar ; Kartiko, Susan ; Manasa, Morgan ; Tay-Lasso, Erika

Background The abdominal seat belt sign (SBS) is associated with an increased risk of hollow viscus injury (HVI). Older age is associated with worse outcomes in trauma patients. Thus, older trauma patients ≥65 years of age (OTPs) may be at an increased risk of HVI with abdominal SBS. Therefore, we hypothesized an increased incidence of HVI and mortality for OTPs vs younger trauma patients (YTPs) with abdominal SBS. Study Design This post hoc analysis of a multi-institutional, prospective, observational study (8/2020-10/2021) included patients >18 years old with an abdominal SBS who underwent abdominal computed tomography (CT) imaging. Older trauma patients were compared to YTPs (18-64 years old) with bivariate analyses. Results Of the 754 patients included in this study from nine level-1 trauma centers, there were 110 (14.6%) OTPs and 644 (85.4%) YTPs. Older trauma patients were older (mean 75.3 vs 35.8 years old, P < .01) and had a higher mean Injury Severity Score (10.8 vs 9.0, P = .02). However, YTPs had an increased abdominal abbreviated-injury scale score (2.01 vs 1.63, P = .02). On CT imaging, OTPs less commonly had intraabdominal free fluid (21.7% vs 11.9%, P = .02) despite a similar rate of abdominal soft tissue contusion ( P > .05). Older trauma patients also had a statistically similar rate of HVI vs YTPs (5.5% vs 9.8%, P = .15). Despite this, OTPs had increased mortality (5.5% vs 1.1%, P < .01) and length of stay (LOS) (5.9 vs 4.9 days P < .01). Conclusion Despite a similar rate of HVI, OTPs with an abdominal SBS had an increased rate of mortality and LOS. This suggests the need for heightened vigilance when caring for OTPs with abdominal SBS.