更新于：2024-11-01

Spider venom poisoning

蜘蛛毒液中毒

更新于：2024-11-01

基本信息

别名

toxic reaction to venom of spider、toxic reaction to venom of spider (diagnosis)

简介-

关联

项与蜘蛛毒液中毒相关的药物

Latrodectus antivenin

靶点-

作用机制

免疫调节剂

在研机构

Instituto Bioclon SA de CV

原研机构

Instituto Bioclon SA de CV

在研适应症

蜘蛛毒液中毒 [+1]

非在研适应症

疼痛 [+1]

最高研发阶段批准上市

首次获批国家/地区

墨西哥

首次获批日期2014-01-01

Antivenin (Latrodectus mactans)(Merck Sharp & Dohme)

靶点-

作用机制

免疫调节剂

在研机构

Merck Sharp & Dohme LLC

原研机构

Merck Sharp & Dohme LLC

在研适应症

蜘蛛毒液中毒

非在研适应症-

最高研发阶段批准上市

首次获批国家/地区

美国

首次获批日期1936-02-13

项与蜘蛛毒液中毒相关的临床试验

CTRI/2024/10/074872 / Not yet recruitingN/AIIT

A randomized controlled trial to evaluate the add on efficacy of Agastya lepa against Tambula hingu lepa in pitta kaphaja luta visa - NIL

开始日期2024-10-15

申办/合作机构-

RBR-7jz7hm / Recruiting临床3期IIT

Effectiveness of the use of topical Tetracycline in cutaneous Loxoscelism - ETTCL: EFFECTIVENESS TOPICAL TETRACYCLINE CUTANEOUS LOXOSCELISM

开始日期2018-10-01

申办/合作机构-

100 项与蜘蛛毒液中毒相关的临床结果

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100 项与蜘蛛毒液中毒相关的转化医学

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0 项与蜘蛛毒液中毒相关的专利（医药）

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项与蜘蛛毒液中毒相关的文献（医药）

2023-08-01·Journal of International Medical Research

Removal Notice

Review

作者: Alian, Shahriar ; Zakariaei, Ashkan ; Zakariaei, Zakaria ; Soleymani, Mostafa ; Fakhar, Mahdi ; Nourzad, Fatemeh

A brown recluse spider (BRS) bite is challenging to confirm, but may be clinically diagnosed by considering the location, the season of the year, and the clinical manifestations. Here, the case of a 26-year-old male who presented after an insect bite with a skin lesion, bruising, severe swelling, and diffuse blisters on the right lower extremity after three days, is described. Following clinical examination, patient history assessment, and consideration of other relevant factors, the patient received a differential diagnosis of necrotizing fasciitis caused by BRS bite. Although spider bite poisoning is rare, proper diagnosis and management are important because, in some cases, the outcomes may be devastating.

2023-06-01·Journal of surgical case reports

Massive dermal ulcerative lesions because of brown recluse spider bite: a rare case report and review of literature.

作者: Zakariaei, Ashkan ; Alian, Shahriar ; Zakariaei, Zakaria ; Nourzad, Fatemeh ; Fakhar, Mahdi

A brown recluse spider (BRS) bite is challenging to confirm, but can be clinically diagnosed by considering the location, the season of the year and the clinical manifestations. We described a 26-year-old male who presented after a BRS bite with a skin lesion, bruising, severe swelling and diffuse blisters on the right lower extremity after 3 days. This case should be considered in the differential diagnosis of necrotizing fasciitis. Although spider bite poisoning is rare, proper diagnosis and management are important because, in some cases, it can have devastating outcomes.

2022-11-01·BMJ Case Reports

Acute necrotic arachnidism with necrotising fasciitis and recurrent pneumothorax

Article

作者: Duggal, Jasleen ; Reddy, Shiva Kumar ; Rao, Swathi Sunil

A male infant presented with swelling of the left leg and fever. Over the next 2 days, the area developed fasciitis extending to the left thigh, abdomen, and lower chest. Meanwhile, the parents found a giant brown spider within the infant’s cot belonging to the genusLoxosceles, otherwise called the brown recluse spider. The dermo-myonecrosis progressed to deeper tissues involving the lung parenchyma requiring invasive ventilation. CT of the thorax showed multiple pneumatoceles, and lung biopsy showed alveolar necrosis. The infant was treated with intravenous antibiotics and corticosteroids. We drained the pneumothoraces by thoracostomy and insertion of intercostal drainage tubes. The infant required respiratory support initially by conventional ventilation, which was escalated to high-frequency oscillatory ventilation. He had refractory hypoxaemia and died. This is the first fatal case of acute spider envenomation described in India. Spider envenomation must be considered in patients with sudden onset, rapidly progressive necrotising fasciitis unresponsive to antibiotic therapy.