Cerebral dopamine neurotrophic factor(University of Helsinki)(Cerebral dopamine neurotrophic factor(University of Helsinki))

概要

基本信息

药物类型

蛋白类药物

别名-

靶点-

作用方式-

作用机制-

治疗领域

神经系统疾病内分泌与代谢疾病

在研适应症-

非在研适应症

帕金森病

原研机构

Herantis Pharma Oyj

在研机构-

非在研机构

Herantis Pharma Oyj

最高研发阶段无进展临床1/2期

首次获批日期-

最高研发阶段(中国)-

特殊审评-

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关联

2

项与 Cerebral dopamine neurotrophic factor(University of Helsinki) 相关的临床试验

NCT03775538

/ Completed临床1/2期

A Randomised, Double-Blind, Multi-centre, Active Treatment, Extension and Safety Study for Patients With Idiopathic Parkinson's Disease (PD) Who Previously Completed the CDNF/DDS Main Study HP-CD-CL-2002

This study is an extension to the HP-CD-CL-2002 clinical study. It evaluates the long-term safety and tolerability of CDNF in patients with Parkinson's disease when dosed directly into the brain using an implanted investigational drug delivery system (DDS). Long-term safety of the DDS is also being evaluated. All patients will receive monthly infusions of either mid- or high-dose of CDNF for a period of 6 months.

开始日期2018-07-05

申办/合作机构

Herantis Pharma Oyj

[+1]

NCT03295786

/ Completed临床1/2期

Phase 1-2, Randomised, Double-Blind, Placebo Controlled, Safety and Tolerability Study of Intraputamenal Cerebral Dopamine Neurotrophic Factor (CDNF) Infusions Via an Investigational Drug Delivery System to Patients With Parkinson's Disease

This study evaluates the safety and tolerability of CDNF in patients with Parkinson's disease, when dosed directly into the brain using an implanted investigational drug delivery system (DDS). Safety and accuracy of the DDS is also being evaluated. One-third of the patients will receive monthly infusions with placebo and two-third of the patients will receive monthly infusions with either mid- or high-doses of CDNF for a period of 6 months.

开始日期2017-09-26

申办/合作机构

Herantis Pharma Oyj

[+1]

100 项与 Cerebral dopamine neurotrophic factor(University of Helsinki) 相关的临床结果

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100 项与 Cerebral dopamine neurotrophic factor(University of Helsinki) 相关的转化医学

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100 项与 Cerebral dopamine neurotrophic factor(University of Helsinki) 相关的专利（医药）

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100 项与 Cerebral dopamine neurotrophic factor(University of Helsinki) 相关的药物交易

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