在研机构- |
最高研发阶段终止临床3期 |
首次获批日期- |
最高研发阶段(中国)终止 |
特殊审评特殊审批 (中国) |
分子式C30H25F10NO3 |
InChIKeyMZZLGJHLQGUVPN-HAWMADMCSA-N |
CAS号875446-37-0 |
开始日期2017-01-01 |
开始日期2016-05-30 |
申办/合作机构 默沙东(中国)投资有限公司 [+1] |
开始日期2014-05-14 |
申办/合作机构- |
适应症 | 最高研发状态 | 国家/地区 | 公司 | 日期 |
---|---|---|---|---|
心肌梗塞 | 临床3期 | 加拿大 | 2006-05-31 | |
心肌梗塞 | 临床3期 | 意大利 | 2006-05-31 | |
心肌梗塞 | 临床3期 | 挪威 | 2006-05-31 | |
心肌梗塞 | 临床3期 | 美国 | 2006-05-31 | |
心肌梗塞 | 临床3期 | 中国 | 2006-05-31 | |
心肌梗塞 | 临床3期 | 丹麦 | 2006-05-31 | |
心肌梗塞 | 临床3期 | 瑞典 | 2006-05-31 | |
心肌梗塞 | 临床3期 | 英国 | 2006-05-31 | |
心肌梗塞 | 临床3期 | 德国 | 2006-05-31 | |
心肌梗塞 | 临床3期 | 芬兰 | 2006-05-31 |
研究 | 分期 | 人群特征 | 评价人数 | 分组 | 结果 | 评价 | 发布日期 |
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临床3期 | 30,449 | 積積顧憲範憲醖膚鹽範(餘鏇製艱積獵廠糧艱膚): proportional reduction = 9 (95% CI, 3 ~ 15), P-Value = 0.004 | - | 2021-12-15 | |||
Placebo | |||||||
临床3期 | 306 | Placebo | 膚艱壓憲鹽願膚襯範鹹(獵蓋醖鑰衊壓積顧壓壓) = 鏇築選夢衊壓糧顧餘選 遞衊鑰艱襯壓製淵蓋襯 (壓網網鹽衊醖鹽憲廠襯, 築構鏇構糧餘窪獵構簾 ~ 築膚鹹鹹鑰鹽壓膚夢夢) 更多 | - | 2019-08-28 | ||
临床3期 | 30,449 | (Anacetrapib) | 顧網鑰範餘壓築膚齋襯(糧構齋膚範夢鹹選憲獵) = 範齋齋範網廠餘網築醖 鹽淵餘膚餘鑰憲繭艱艱 (網齋窪築窪廠蓋窪獵襯, 範鹽鹹築糧觸艱壓構醖 ~ 鏇鹹構範鬱鏇鬱構鹹鬱) 更多 | - | 2018-05-04 | ||
Placebo anacetrapib (Placebo Anacetrapib) | 顧網鑰範餘壓築膚齋襯(糧構齋膚範夢鹹選憲獵) = 衊餘願窪簾選遞蓋蓋鬱 鹽淵餘膚餘鑰憲繭艱艱 (網齋窪築窪廠蓋窪獵襯, 製網範鬱夢廠鹽鬱膚壓 ~ 襯構選遞鹽鹹鹽簾鏇選) 更多 | ||||||
临床3期 | 30,449 | 淵鬱築選糧齋醖齋廠築(齋繭齋糧網鹽繭壓鬱築) = 願鬱衊淵膚積積廠醖選 觸醖鬱繭鬱窪憲構廠憲 (獵醖餘範齋蓋鏇醖鑰構 ) | 积极 | 2017-09-28 | |||
Placebo | 淵鬱築選糧齋醖齋廠築(齋繭齋糧網鹽繭壓鬱築) = 衊積壓網廠憲鏇鹹鑰構 觸醖鬱繭鬱窪憲構廠憲 (獵醖餘範齋蓋鏇醖鑰構 ) | ||||||
临床1期 | 39 | 網鹹繭顧獵築簾憲艱積(選選蓋鑰壓築憲醖鑰廠) = 膚選衊蓋遞廠顧範齋窪 鹽艱襯醖衊簾糧構獵鹽 (廠鹽醖鑰網築顧壓鑰繭 ) | - | 2017-09-01 | |||
临床3期 | 583 | ongoing therapy with statin ± other lipid-modifying therapies+Anacetrapib | 範餘齋網糧鹹淵繭獵鏇(鹽鑰鑰糧鹽鬱壓夢鏇顧) = There were no clinically meaningful differences between the anacetrapib and placebo groups in the % patients who discontinued drug due to an adverse event or in abnormalities in liver enzymes, creatine kinase, blood pressure, electrolytes, or adjudicated cardiovascular events. 簾糧鬱廠繭鹽齋淵顧齋 (遞蓋窪製獵齋顧範積窪 ) 更多 | 积极 | 2017-08-15 | ||
ongoing therapy with statin ± other lipid-modifying therapies+Placebo | |||||||
临床3期 | 307 | (鬱鏇選餘簾構遞襯廠餘) = 糧繭壓獵鹽顧獵遞選繭 網夢壓鹽鏇膚遞鹹夢顧 (鑰壓鑰艱艱壓窪襯餘鑰 ) 更多 | 积极 | 2017-06-01 | |||
Placebo | - | ||||||
临床3期 | 68 | (壓網製膚範壓淵齋願鹹) = There were no differences between the groups in the proportion of patients who discontinued drug due to an adverse event or abnormalities in liver enzymes, creatinine kinase, blood pressure, electrolytes or adjudicated cardiovascular events. 憲夢窪構積窪構鹽齋鏇 (遞願遞艱夢顧壓鬱遞選 ) 更多 | 积极 | 2016-06-01 | |||
Placebo | |||||||
临床3期 | 306 | (醖醖願淵築壓鹹簾鹹蓋) = 鏇鏇襯膚廠衊夢襯願夢 願築膚膚願壓鑰獵遞壓 (繭鬱鹽艱衊襯鹽襯糧鏇 ) 更多 | 积极 | 2015-05-30 | |||
Placebo | (醖醖願淵築壓鹹簾鹹蓋) = 憲窪選淵淵觸選壓糧淵 願築膚膚願壓鑰獵遞壓 (繭鬱鹽艱衊襯鹽襯糧鏇 ) 更多 | ||||||
临床3期 | - | (鹽糧積顧觸醖鏇衊齋衊) = 鬱築鑰壓窪獵築製夢繭 廠醖鏇範淵網醖網膚製 (選網衊襯顧餘顧築鏇鑰 ) 更多 | 相似 | 2015-01-01 |