Pyrimidine linked acyl thiourea derivatives 6j(Quaid-I-Azam University)(Pyrimidine linked acyl thiourea derivatives 6j(Quaid-I-Azam University))

概要

基本信息

药物类型

小分子化药

别名-

靶点

AMYs

作用机制

α-淀粉酶抑制剂

治疗领域

感染

在研适应症

细菌感染

非在研适应症-

原研机构

Quaid-i-Azam University

在研机构

Quaid-i-Azam University

非在研机构-

最高研发阶段临床前

首次获批日期-

最高研发阶段(中国)-

特殊审评-

关联

100 项与 Pyrimidine linked acyl thiourea derivatives 6j(Quaid-I-Azam University) 相关的临床结果

登录后查看更多信息

100 项与 Pyrimidine linked acyl thiourea derivatives 6j(Quaid-I-Azam University) 相关的转化医学

登录后查看更多信息

100 项与 Pyrimidine linked acyl thiourea derivatives 6j(Quaid-I-Azam University) 相关的专利（医药）

登录后查看更多信息

1

项与 Pyrimidine linked acyl thiourea derivatives 6j(Quaid-I-Azam University) 相关的文献（医药）

RSC Advances

Novel pyrimidine linked acyl thiourea derivatives as potent α-amylase and proteinase K inhibitors: design, synthesis, molecular docking and ADME studies

Article

作者: Latif, Muhammad ; Zaman, Hina ; Ismail, Hammad ; Saeed, Aamer ; Anwaar, Sadaf ; Hashmi, Muhammad Zaffar ; El-Seedi, Hesham R.

To discover promising therapeutic agents, novel diaryl pyrimidine linked acyl thiourea derivatives (6a–j) were designed and synthesized via straightforward and multistep synthesis.

100 项与 Pyrimidine linked acyl thiourea derivatives 6j(Quaid-I-Azam University) 相关的药物交易

登录后查看更多信息