Various kinds of non-hormonal or hormonal treatment of hirsutism with the description of medication effect spot, clinical effect and possible complications are described. The necessity for carrying out this therapy in combination with cosmetic interventions because of aesthetical reasons, as well as possible effect of androgenic hormones on subsequent fertility are emphasized. The effects of contraceptives, corticosteroides, spironolactones, ketoconazoles, GnRH agonists, flutamides, finasterides, somatostatine analogues, H2 receptors blockers, thyroid gland hormones and cyproterone acetates are shown.