胆维丁(Cholecalciferol Chloesterol) - 在研适应症：骨质疏松症，佝偻病_专利_临床

概要

基本信息

药物类型

小分子化药

别名

英康利

靶点-

作用机制-

治疗领域

内分泌与代谢疾病皮肤和肌肉骨骼疾病

在研适应症

骨质疏松症佝偻病

非在研适应症-

原研机构

苏州第壹制药有限公司

在研机构

苏州第壹制药有限公司

非在研机构-

最高研发阶段批准上市

首次获批日期

中国 (1982-01-01),

骨质疏松症佝偻病

最高研发阶段(中国)批准上市

特殊审评-

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结构

分子式C28H46O

InChIKeyDIPPFEXMRDPFBK-JPWDPSJFSA-N

CAS号511-28-4

关联

1

项与胆维丁相关的临床试验

NCT01845142 / Completed临床4期IIT

Immunologic Functions of a Single Dose of 100.000 I.U. Cholecalciferol (Vitamin D3)

Vitamin D receptors are expressed in activated different immune cells. It is not known, which immune cell type is targeted by exogenous vitamin D. Here, vitamin D-deficient individuals will receive once 100.000 I.U. vitamin D3 either intramuscular or subcutaneous in a double-blind placebo controlled setting. Immune cells will be monitored from the blood over time.

开始日期2013-02-01

申办/合作机构

Charité - Universitätsmedizin Berlin

100 项与胆维丁相关的临床结果

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100 项与胆维丁相关的转化医学

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100 项与胆维丁相关的专利（医药）

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2

项与胆维丁相关的文献（医药）

1971-01-25·FEBS Letters3区 · 生物学

The metabolism of cholesterol by the echinoderms Aterias rubens and Solaster papposus

3区 · 生物学

Article

作者: L.J. Goad ; A.G. Smith

When 4-14C-labeled cholesterol (I) was injected into the echinoderm A. rubens, it was metabolized to cholest-7-enol, 5α-cholestanol, 7α,8α-epoxycholestanol, and 5α,6α-epoxycholestanol.Similar results were obtained following injection of S. papposus with 4-14C-labeled I for 9 days.

1971-01-01·The Kurume Medical Journal

THE EFFECT OF ADENOSINE AND B2-TETRABUTYRATE ON HIGH LIPID BLOOD ANIMALS

Article

作者: Tadashi Arima ; Seiichiro Yamasaki

Rabbits were fed 100 g/day of a standard ration containing 1% chloesterol.One group of 5 was supplemented with 20 mg/kg/day of adenosine and 8.5 mg/day vitamin B2 tetrabutyrate.Another group was supplemented with 8.5 mg/day of vitamin B2 tetrabutyrate, and a third group was given only the cholesterol-fortified ration.After 6-weeks feeding the change in vitamin B2 quantity in liver, kidney, and heart was measured and total cholesterol, phospholipid triglyceride, lipid peroxide, and protein were determined in the blood.Both adenosine and vitamin B2-tetrabutyrate treatment significantly raised vitamin B2 levels over controls, the joint administration giving higher levels than with vitamin B2 tetrabutyrate alone.

100 项与胆维丁相关的药物交易

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