过氧化氢(Hydrogen Peroxide) - 在研适应症：伤口感染，牙周附着丢失，牙周感染_专利_临床

概要

基本信息

药物类型

小分子化药

别名

ESKATA、ESKERIELE、hydrogen peroxide

+ [2]

靶点-

作用机制

细胞凋亡刺激剂

治疗领域

感染口颌疾病

在研适应症

伤口感染牙周附着丢失牙周感染+ [1]

非在研适应症

寻常痤疮黑色丘疹性皮病脂溢性角化病+ [2]

原研机构

天津市东方广诚医药化工有限公司

在研机构

Krishnadevaraya College of Dental Sciences and Hospital天津市东方广诚医药化工有限公司

非在研机构

JDC Tech Co. Ltd.

Aclaris Therapeutics, Inc.

Dermata Therapeutics, Inc.

最高研发阶段批准上市

首次获批日期

中国 (1981-01-01),

伤口感染

最高研发阶段(中国)批准上市

特殊审评-

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关联

72

项与过氧化氢相关的临床试验

CTRI/2023/12/060472 / Not yet recruitingN/AIIT

Effectiveness of hydrogen peroxide solution on oral hygiene among patients admitted in ICU of selected hospitals of Gangtok, Sikkim - NIL

开始日期2023-12-11

申办/合作机构-

CTRI/2023/12/060415 / Recruiting临床2期

Internal Bleaching : Comparing the effectiveness of Opalescence Endo and Hydrogen Peroxide with Sodium Perborate.

开始日期2023-12-10

申办/合作机构-

IRCT20120215009014N489 / Suspended临床3期

Effect of topical solution hydrogen peroxide 40% versus cryotherapy on the treatment of seborrheic keratosis lesions: a single-blind randomized clinical trial

开始日期2023-11-22

申办/合作机构

Hamedan University of Medical Sciences

100 项与过氧化氢相关的临床结果

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100 项与过氧化氢相关的转化医学

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100 项与过氧化氢相关的专利（医药）

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7,273

项与过氧化氢相关的文献（医药）

2024-05-01·Neural regeneration research

The miR-9-5p/CXCL11 pathway is a key target of hydrogen sulfide-mediated inhibition of neuroinflammation in hypoxic ischemic brain injury.

Article

作者: Li, Tong ; Xin, Danqing ; Gai, Chengcheng ; Wang, Zhen ; Yu, Shuwen ; Jiang, Zige ; Liu, Dexiang ; Zhao, Yijing ; Li, Tingting

We previously showed that hydrogen sulfide (H₂S) has a neuroprotective effect in the context of hypoxic ischemic brain injury in neonatal mice. However, the precise mechanism underlying the role of H₂S in this situation remains unclear. In this study, we used a neonatal mouse model of hypoxic ischemic brain injury and a lipopolysaccharide-stimulated BV2 cell model and found that treatment with L-cysteine, a H₂S precursor, attenuated the cerebral infarction and cerebral atrophy induced by hypoxia and ischemia and increased the expression of miR-9-5p and cystathionine β synthase (a major H₂S synthetase in the brain) in the prefrontal cortex. We also found that an miR-9-5p inhibitor blocked the expression of cystathionine β synthase in the prefrontal cortex in mice with brain injury caused by hypoxia and ischemia. Furthermore, miR-9-5p overexpression increased cystathionine-β-synthase and H₂S expression in the injured prefrontal cortex of mice with hypoxic ischemic brain injury. L-cysteine decreased the expression of CXCL11, an miR-9-5p target gene, in the prefrontal cortex of the mouse model and in lipopolysaccharide-stimulated BV-2 cells and increased the levels of proinflammatory cytokines BNIP3, FSTL1, SOCS2 and SOCS5, while treatment with an miR-9-5p inhibitor reversed these changes. These findings suggest that H₂S can reduce neuroinflammation in a neonatal mouse model of hypoxic ischemic brain injury through regulating the miR-9-5p/CXCL11 axis and restoring β-synthase expression, thereby playing a role in reducing neuroinflammation in hypoxic ischemic brain injury.

2024-03-01·International Journal of Medical Microbiology

Polyhexanide based contact lens storage fluids frequently exhibit insufficient antifungal activity against Fusarium species

Article

作者: Kampik, Daniel ; Theuersbacher, Johanna ; Zimmermann, Anna ; Walther, Grit ; Schrenker, Benedikt ; Koch, Thorsten ; Kurzai, Oliver ; Martin, Ronny

PURPOSE:

Fusarium keratitis is a severe infection of the anterior eye, frequently leading to keratoplasty or surgical removal of the affected eye. A major risk factor for infection is the use of contact lenses. Inadequate hygiene precautions and mold-growth permissive storage fluids are important risk factors for fungal keratitis. The aim of this study was to comparatively analyze contact lens storage fluids disinfection efficacy against Fusarium species.

METHODS:

Eleven commercially available storage fluids were tested. The storage fluids were classified according to their active ingredients myristamidopropyldimethylamine (Aldox), polyhexanide and hydrogen peroxide. Efficacy was tested against isolates belonging to the Fusarium solani and Fusarium oxysporum species complexes as the most common agents of mould keratitis. Tests were carried out based on DIN EN ISO 14729.

RESULTS:

All Aldox and hydrogen peroxide (H₂O₂) based fluids were effective against Fusarium spp., while the majority of polyhexanide based storage fluids showed only limited or no antifungal effects. Efficacy of polyhexanide could be restored by the addition of the pH-regulating agent tromethamine - an additive component in one commercially available product.

CONCLUSIONS:

In summary, the use of Aldox- or hydrogen peroxide-based storage fluids may reduce the risk of Fusarium keratitis, while polyhexanide-based agents largely lack efficacy against Fusarium.

2024-03-01·Journal of Hazardous Materials

Quorum sensing signal autoinducer-2 promotes hydrogen peroxide degradation in water by Gram-positive bacteria

Article

作者: Wang, Hailei ; Gao, Chao ; Li, Yi ; Qin, Mengyuan ; Niu, Wenfang ; Han, Jingjing ; Han, Shuo ; Wang, Yuqi

Hydrogen peroxide is widely used to remedy bacterial and parasitic infections, but its excessive use will cause severe damage to aquatic animals. Moreover, there is no safe, efficient and low-cost method to degrade residual hydrogen peroxide in water. Here we developed a hydrogen peroxide removal mechanism by which autoinducer-2 (AI-2), a quorum sensing signal molecule that can promote the hydrogen peroxide degradation by Gram-positive bacteria. Here, we investigated the promotion effect of AI-2 on hydrogen peroxide degradation by Deinococcus sp. Y35 and the response of the antioxidant system. We further sought to understand the key mechanism underlying the promotion effect of AI-2 on hydrogen peroxide degradation is that, AI-2 contributed to the resistance of strain Y35 to oxidative stress induced by hydrogen peroxide, and altered membrane permeability of strain Y35 that allowed more hydrogen peroxide to enter bacterial cells and be degraded. Additionally, AI-2 can also encourage multiple Gram-positive bacteria to degrade hydrogen peroxide. Accordingly, our study serves as a reference for the regulation mechanism of the signal molecule AI-2 and provides the development of new strategies for hydrogen peroxide degradation.

69

项与过氧化氢相关的新闻（医药）

2024-03-11

·GlobeNewswire-Health Care

Study on Foot-and-Mouth Disease Virus Results in Submission for Additional EPA Label

FREDERICK, Md., March 11, 2024 (GLOBE NEWSWIRE) -- TOMI Environmental Solutions, Inc.® (“TOMI”) (NASDAQ: TOMZ), a global company specializing in disinfection and decontamination solutions, announces a new groundbreaking study demonstrating the effectiveness of its solutions against foot-and-mouth disease virus (FMDV). This significant advancement supports the Company’s submission for an additional EPA label. Foot-and-mouth disease (FMD) represents a critical global threat, being an extremely contagious disease affecting a wide range of cloven-hoofed animals including cows, pigs, sheep, goats, and deer. The rapid spread of FMDV among livestock can lead to significant economic losses and disrupt international trade if not promptly and effectively controlled. TOMI’s recent study has proven SteraMist iHP technology to eliminate infectious FMDV from both porous (concrete) and non-porous (stainless steel) surfaces in the presence of organic soil load. This achievement meets the stringent EPA standards for demonstrating virucidal efficacy. The study, conducted by the Department of Homeland Security (DHS) Science and Technology Directorate’s (S&T’s) Plum Island Animal Disease Center (PIADC), adhered to the strict regulatory guidelines of the U.S. Select Agent Program and utilized methods aligned with EPA-approved testing standards. Dr. Halden Shane, CEO of TOMI, emphasizes the critical nature of combating Transboundary Animal Disease (TAD) outbreaks, such as FMD, “These diseases not only disrupt domestic agricultural production but may also severely impact international trade of agricultural commodities. TADs have the potential to cause widespread economic and societal damage, particularly in regions where agricultural animals are a primary livelihood. Our mission extends into the food safety sector, aiming to halt the transmission of viruses and prevent cross-contamination. This latest study underscores our commitment to providing effective solutions in the fight against global animal diseases," Dr. Halden Shane remarked. TOMI continues conducting research to strengthen its role as a crucial advocate for advancing global health and ensuring food safety, protecting against infectious diseases. TOMI™ Environmental Solutions, Inc.: Innovating for a safer world® TOMI™ Environmental Solutions, Inc. (NASDAQ: TOMZ) is a global decontamination and infection prevention company, providing environmental solutions for disinfection through the manufacturing, sales and licensing of its premier Binary Ionization Technology ® (BIT™) platform. Invented under a defense grant in association with the Defense Advanced Research Projects Agency (DARPA) of the U.S. Department of Defense, BIT™ solution utilizes a low percentage hydrogen peroxide as its only active ingredient and uses patented ionized Hydrogen Peroxide (iHP™) technology in all SteraMist systems to create superior disinfection. TOMI products are designed to service a broad spectrum of use sites, including, but not limited to, hospitals and medical facilities, biosafety labs, pharmaceutical facilities, commercial and office buildings, schools, restaurants, meat and produce processing facilities, and police and fire departments. For additional information, please visit http://www.steramist.com/ or contact us at info@tomimist.com Safe Harbor Statement under the Private Securities Litigation Reform Act of 1995 This press release contains forward-looking statements that are based on current expectations, estimates, forecasts and projections of future performance based on management’s judgment, beliefs, current trends, and anticipated product performance. These forward-looking statements include, without limitation, statements relating to the ability of TOMI’s products to eliminate infectious diseases. Forward-looking statements involve risks and uncertainties that may cause actual results to differ materially from those contained in the forward-looking statements. These factors include, but are not limited to, the impact of COVID-19 pandemic on our business and customers; our ability to maintain and manage growth and generate sales, our reliance on a single or a few products for a majority of revenues; the general business and economic conditions; and other risks as described in our SEC filings, including our Annual Report on Form 10-K for the fiscal year ended March 2023 filed by us with the SEC and other periodic reports we filed with the SEC. The information provided in this document is based upon the facts and circumstances known at this time. Other unknown or unpredictable factors or underlying assumptions subsequently proving to be incorrect could cause actual results to differ materially from those in the forward-looking statements. Although we believe that the expectations reflected in the forward-looking statements are reasonable, we cannot guarantee future results, level of activity, performance, or achievements. You should not place undue reliance on these forward-looking statements. All information provided in this press release is as of today’s date, unless otherwise stated, and we undertake no duty to update such information, except as required under applicable law. INVESTOR RELATIONS CONTACT: John Nesbett/Rosalyn ChristianIMS Investor Relationstomi@imsinvestorrelations.com

2024-03-06

·PRNewswire

Synexis® LLC. Introduces Sentry XL, Expanding Indoor Environmental Quality Solutions

New device provides largest square footage coverage in IEQ technology LENEXA, Kan., March 6, 2024 /PRNewswire/ -- Synexis is excited to introduce the Sentry XL, our latest product designed to offer exceptional performance and expanded coverage, transforming the way we experience living and working in larger occupied spaces. Continue Reading The Sentry XL is the newest technology offering from Synexis®, a leader in creating cleaner indoor environments. Synexis is the sole developer of patented technology that creates and continuously deploys Dry Hydrogen Peroxide (DHP®) to help reduce the presence of viruses, bacteria, mold and VOCs in the air and on surfaces. The Synexis® Sentry XL provides DHP® coverage for 3,000 square feet, double the previous version. The Sentry XL joins the Synexis portfolio of Indoor Environmental Quality (IEQ) devices using a patented and advanced technology to continuously combat harmful pathogens in the air and on surfaces. Synexis technology converts naturally occurring oxygen and humidity into Dry Hydrogen Peroxide (DHP®). DHP circulates throughout occupied spaces, actively reducing bacteria, mold, viruses, and Volatile Organic Compounds (VOCs) continuously and at the point of introduction. In addition to protecting the largest area in the Synexis portfolio, the Sentry XL provides extended temperature range, a longer-lasting LED bulb, a robust design, and simplified maintenance. The Sentry XL operates as a stand-alone device or can be conveniently wall-mounted requiring only a standard 120VAC outlet to function. "We are excited to introduce the Sentry XL as the latest addition to our expanding product portfolio. With significantly expanded area coverage, and enhanced temperature ranges, this device represents Synexis' commitment to continued investment in innovation and the needs of our customers," said Dennis Doyle, CEO of Synexis. Key Features of the Sentry XL: Maximum Coverage: Effectively safeguards indoor areas of up to 3,000 square feet. Increased Temperature Range: Generates DHP in colder environments as low as 35 degrees Fahrenheit. Extended LED Bulb: An energy–efficient LED bulb with a lifespan over five years, reducing the need for frequent replacements and contributing to cost savings. Robust Design: Crafted from high-quality materials, the Sentry XL is housed in a stainless-steel and aluminum frame, ensuring durability and reliability in challenging indoor conditions. The Sentry XL is now available from Synexis and for more information please visit our website: About Synexis The Synexis® mission since 2008 has been to make the air we breathe and the surfaces we touch continuously cleaner. Synexis is the industry leader in microbial reduction. Our innovative Dry Hydrogen Peroxide (DHP®) fights viruses, bacteria, mold, VOCs, and more. The technology can safely run 24/7/365 within occupied spaces. The Sentry XL can help customers meet the ASHRAE 241 Standard. Synexis® devices provide DHP® coverage to more than 40 million square feet of indoor spaces in a variety of industries such as Healthcare, Education, Sports & Recreation, Food Services, and many more. Our Synexis Systems are regulated by the U.S. Environmental Protection Agency and state governments. Synexis devices are produced in EPA registered facilities and packaged and labeled in accordance with EPA regulations appearing at 40 CFR 152.500. The effectiveness of our DHP technology is supported by data from many peer-reviewed studies. Synexis is the solution for a healthy indoor environment, making the air we breathe and the surfaces we touch cleaner. SOURCE Synexis LLC

2024-02-22

·Science Daily

Compound vital for all life likely played a role in life's origin

A chemical compound essential to all living things has been synthesized in a lab in conditions that could have occurred on early Earth, suggesting it played a role at the outset of life. A chemical compound essential to all living things has been synthesised in a lab in conditions that could have occurred on early Earth, suggesting it played a role at the outset of life, finds a new study led by UCL researchers. The compound, pantetheine, is the active fragment of Coenzyme A. It is important for metabolism -- the chemical processes that maintain life. Earlier studies failed to synthesise pantetheine effectively, leading to suggestions that it was absent at life's origin. In the new study, published in the journal Science, the research team created the compound in water at room temperature using molecules formed from hydrogen cyanide, which was likely abundant on early Earth. Once formed, the researchers said, it is simple to envisage how pantetheine might have aided chemical reactions that led from simple forerunners of protein and RNA molecules to the first living organisms -- a moment that is thought to have occurred 4 billion years ago. The study challenges the view among some researchers in the field that water is too destructive for life to originate in it and that life more likely originated in pools that periodically dried out. Driving the reactions that produced pantetheine were energy-rich molecules called aminonitriles, which are closely chemically related to amino acids, the building blocks of proteins and of life. Members of the same team, led by Professor Matthew Powner (UCL Chemistry), have already used similar chemistry powered by aminonitriles to demonstrate how other key biological ingredients could be created at the origin of life, including peptides (protein-creating chains of amino acids) and nucleotides (the building blocks of RNA and DNA). Professor Powner, senior author of the paper, said: "This new study is further evidence that the basic structures of biology, the primary molecules that biology is built from, are predisposed to form through nitrile chemistry. "The ease with which different classes of biological molecules can be made using nitriles has convinced me that, rather than life being preceded by one molecule such as RNA, and there being an 'RNA world' before life began, the basic molecules of biology emerged alongside each other -- a network of RNAs, proteins, enzymes and cofactors leading to the first living organisms. "Our future work will look at how these molecules came together, how pantetheine chemistry talks to RNA, peptide and lipid chemistry for instance, to deliver chemistry that the individual classes of molecule could not deliver in isolation." A notable earlier attempt to synthesise pantetheine was made in 1995 by the late American chemist Stanley Miller, who had started the field of origin of life experiments three decades earlier, creating amino acids from four simple chemicals in glass tubes. However, in the later 1995 experiment, the yields of pantetheine were very low and required extremely high concentrations of chemicals that had been dried out and sealed in an airtight tube before they were heated to 100 degrees Centigrade. Dr Jasper Fairchild (UCL Chemistry), a lead author of the study, who conducted the work as part of his PhD, said: "The major difference between Miller's study and ours is whereas Miller tried to use acid chemistry, we used nitriles. It's the nitriles that bring the energy and the selectivity. Our reactions just run in water and produce high yields of pantetheine with relatively low concentrations of chemicals needed." Professor Powner added: "It had been assumed you should make these molecules from acids, because using acids appears to be biological, and that is what we are taught at school and at university. We are taught peptides are made from amino acids. "Our work suggests this conventional view has ignored an essential ingredient, the energy required to forge new bonds. The reactions look a little different with nitriles but the end products -- the basic units of biology -- are indistinguishable whether formed through acid or nitrile chemistry." While the paper focuses solely on the chemistry, the research team said that the reactions they demonstrated could plausibly have taken place in pools or lakes of water on the early Earth (but not likely in the oceans as the concentrations of the chemicals would likely be too diluted). The new study was supported by the Engineering and Physical Sciences Research Council, the Simons Foundation and the Volkswagen Foundation. As a result of his work on the origins of life, Professor Powner was named a finalist in the 2021 Blavatnik Awards for Young Scientists. The awards are for scientists aged 42 or younger whose research "is already transforming technology and our understanding of the world."

100 项与过氧化氢相关的药物交易

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研发状态

适应症	最高研发状态	国家/地区	公司
伤口感染	批准上市	中国更多	天津市东方广诚医药化工有限公司更多
牙周感染	临床1期	印度更多	Krishnadevaraya College of Dental Sciences and Hospital 更多
黑色丘疹性皮病	无进展	美国更多	Aclaris Therapeutics, Inc. 更多
可见病灶	无进展	美国更多	Aclaris Therapeutics, Inc. 更多
寻常痤疮	无进展	美国更多	Dermata Therapeutics, Inc. 更多

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临床结果

适应症

分期

评价

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研究	分期	人群特征	评价人数	分组	结果	评价	发布日期


NCT03812510 (CTgov)	临床3期	疣	426	hydrogen peroxide (A-101 45% (Active))	鬱繭襯遞衊憲鹽願積築(製積構範襯顧醖鏇顧夢) = 築窪鏇膚齋齋壓窪齋積醖獵獵製糧壓齋壓窪壓 (繭糧鹽繭製製積糧餘壓, 鑰淵糧壓顧範齋衊鏇餘 ~ 簾繭積遞獵觸壓蓋廠築) 更多	-	2020-11-23
				isopropyl alcohol (Isopropyl Alcohol and Water (Vehicle))	鬱繭襯遞衊憲鹽願積築(製積構範襯顧醖鏇顧夢) = 夢鏇鬱蓋壓繭艱壓憲築醖獵獵製糧壓齋壓窪壓 (繭糧鹽繭製製積糧餘壓, 衊艱選鹽衊壓蓋選構壓 ~ 獵蓋製鹹獵觸積艱簾齋) 更多
NCT03691831 (CTgov)	临床3期	疣	502	Active (Active)	衊蓋夢簾製膚構網糧夢(遞醖糧衊衊鹹鹹觸廠壓): Odds Ratio (OR) = 4.80 (95% CI, 2.14 ~ 10.76), P-Value = 0.0001 更多	-	2020-10-05
				Vehicle (Vehicle)
NCT03687372 (CTgov)	临床3期	疣	503	vehicle	醖積選鏇鏇壓願構構鏇(蓋夢窪製鏇淵廠齋醖觸) = 構鹽廠蓋鏇遞製糧鬱鏇廠願憲顧範艱築獵糧襯 (顧衊鹽繭選鏇夢艱夢鏇, 壓壓蓋憲鹽範齋築構築 ~ 艱艱鏇窪願築積夢鑰鏇) 更多	-	2020-10-05
NCT03224598 (CTgov)	临床2期	黑色丘疹性皮病	39	A-101 Topical Solution 40% (No Medical Abrading)	簾齋鏇鑰壓鏇選觸觸築(獵淵觸鬱憲鹹窪鹽衊餘) = 網鹹壓觸選糧襯獵構襯鹽選餘積鏇鬱築範膚鬱 (繭積簾簾鑰蓋顧顧醖衊, 鏇鏇餘簾獵網蓋醖築製 ~ 繭觸積淵觸觸壓鹹壓糧) 更多	-	2020-03-17
				A-101 Topical Solution 40% (Medically Abrading)	簾齋鏇鑰壓鏇選觸觸築(獵淵觸鬱憲鹹窪鹽衊餘) = 憲願醖窪獵構觸網鬱艱鹽選餘積鏇鬱築範膚鬱 (繭積簾簾鑰蓋顧顧醖衊, 夢糧觸築網製選膚衊觸 ~ 壓窪齋壓遞獵簾構積網) 更多
NCT03487588 (CTgov)	临床4期	脂溢性角化病	41	A-101 Topical Solution	餘艱廠窪鹹鬱襯遞糧積(鑰襯鏇製範範夢膚網鹹) = 壓夢壓糧範鬱鹽網糧憲選糧襯鹹網壓膚衊構網 (淵觸願餘鏇簾積鹽鹹繭, 製積窪憲壓齋選膚夢衊 ~ 網夢網鬱鑰艱壓鏇選憲) 更多	-	2019-10-02
ERS2019	N/A	-	-	Hydrogen peroxide (H2O2)	艱襯願餘襯夢鏇糧鏇醖(淵網齋鹽窪艱蓋鏇觸窪) = 範顧簾壓膚夢壓衊簾醖壓鑰憲鏇襯淵鬱壓獵醖 (夢齋夢顧鑰構積蓋衊壓 )	-	2019-09-28
NCT03148691 (CTgov)	临床2期	脂溢性角化病	253	A-101 (Vehicle)	積艱構觸願廠構鬱觸壓(選鏇憲鹹構糧鑰鹹夢壓) = 積醖鑰選獵淵廠醖選艱蓋構鑰壓鹽憲製鑰憲壓 (鹹網製齋鏇製齋齋蓋壓, 蓋襯衊顧蓋艱願鏇顧範 ~ 醖夢鹽鹹襯獵壓夢壓廠) 更多	-	2019-05-06
				A-101 (A-101 Low Dose)	積艱構觸願廠構鬱觸壓(選鏇憲鹹構糧鑰鹹夢壓) = 網獵鑰糧簾選壓蓋糧齋蓋構鑰壓鹽憲製鑰憲壓 (鹹網製齋鏇製齋齋蓋壓, 齋構糧鬱廠糧鬱壓鏇鹽 ~ 網積壓醖襯淵構餘衊網) 更多
NCT03210337 (CTgov)	临床2期	疣	157	A-101 Topical Solution (Active)	廠艱廠齋鏇壓遞繭窪艱(憲衊範獵衊襯蓋艱網範) = 醖網網鏇顧鏇顧夢夢願齋鹹築獵鬱襯餘觸廠積 (鹽窪廠艱製廠鹹繭網蓋, 廠淵憲築積鹽選顧衊鬱 ~ 醖壓窪顧醖觸顧範範鹹) 更多	-	2019-05-01
				A-101 Vehicle Solution (Vehicle)	廠艱廠齋鏇壓遞繭窪艱(憲衊範獵衊襯蓋艱網範) = 範襯糧壓憲夢鹽壓鬱顧齋鹹築獵鬱襯餘觸廠積 (鹽窪廠艱製廠鹹繭網蓋, 鑰齋積壓積繭鬱鏇夢壓 ~ 窪蓋顧顧鏇齋膚壓鏇積) 更多
NCT03278028 (CTgov)	临床2期	疣	159	A-101 Topical Solution (Active)	鑰醖鹹構醖積範獵衊觸(鹽選選鑰窪糧鹹襯衊艱) = 構繭構鑰築製蓋鹽範構醖獵夢鑰觸選網製夢糧 (顧餘築廠繭繭蓋襯獵簾, 製鏇簾夢糧壓齋鏇憲範 ~ 築蓋鏇廠鏇獵鹹顧餘鬱) 更多	-	2019-03-29
				A-101 Vehicle Solution (Vehicle)	鑰醖鹹構醖積範獵衊觸(鹽選選鑰窪糧鹹襯衊艱) = 鏇鏇願糧襯鬱鬱衊構觸醖獵夢鑰觸選網製夢糧 (顧餘築廠繭繭蓋襯獵簾, 夢鬱鏇糧願網獵願衊衊 ~ 築遞遞夢範製獵齋鏇簾) 更多
NCT01986920 (CTgov)	临床1/2期	脂溢性角化病	35	A-101 25% (A-101 25%)	鬱鹹繭糧鏇願積築衊蓋(簾糧網淵築觸鬱膚築鑰) = 醖鹽鹹繭選鬱構壓餘願鹽範鹽簾顧憲蓋繭鹽艱 (願觸顧鹽衊鏇網網壓鏇, 簾選繭餘願餘鑰選齋積 ~ 壓鑰鹹淵蓋網膚壓鏇顧) 更多	-	2018-12-11
				A-101 32.5% (A-101 32.5%)	鬱鹹繭糧鏇願積築衊蓋(簾糧網淵築觸鬱膚築鑰) = 窪觸網範遞壓簾願窪獵鹽範鹽簾顧憲蓋繭鹽艱 (願觸顧鹽衊鏇網網壓鏇, 襯襯選憲積顧顧選衊壓 ~ 網繭鹽壓鏇憲鹽遞壓鹹) 更多