预约演示
更新于：2025-04-05
Apocyanin
香草乙酮
更新于：2025-04-05
概要
基本信息
结构/序列
分子式C9H10O3 |
InChIKeyDFYRUELUNQRZTB-UHFFFAOYSA-N |
CAS号498-02-2 |
关联
8
项与 香草乙酮 相关的临床试验CTIS2023-508791-11-00
A placebo-controlled, double-blinded, randomized, dose-finding trial using a combination of apocynin and paeonol (APPA) for the treatment of knee osteoarthritis
EUCTR2020-000249-14-DK
A placebo-controlled, double-blinded, randomized, trial using a combination of apocynin and paeonol (APPA) for the treatment of knee osteoarthritis
IRCT20200418047122N1
Evaluation of the protective effect of a combination drug including Apocynin, Niacin, and Tannin on prevention of cardiovascular and respiratory morbidities and mortality in COVID-19 infection: A Clinical Trial
100 项与 香草乙酮 相关的临床结果
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100 项与 香草乙酮 相关的转化医学
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100 项与 香草乙酮 相关的专利（医药）
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6,393
项与 香草乙酮 相关的文献（医药）2025-06-01SEPARATION AND PURIFICATION TECHNOLOGY
Catalytic oxidative depolymerization of lignin to aromatic compounds using transition metal doped ionic Liquid-based polyoxometalate catalysts
作者: Shi, Junyou ; Zhao, Luyao ; Zhang, Yu ; Deng, Haoyu ; Xu, Wenbiao ; Li, Mingfei
Significant attention has been focused on the depolymerization of lignin into monophenolics, as lignin is the most abundant biomass feedstock, and its valorization is considered crucial for a complete biomass refinery.In this study, we investigate catalytic oxidative depolymerization using novel bimetallic transition metal (Ni and Co) doped ionic liquid-polyoxometalate (ILPOM) composites under aerobic conditions.We systematically evaluate various catalysts, including [MIMPS]H2PW12O40, Ni[MIMPS]PW12O40, Co[MIMPS]PW12O40, [MIMPS]H2PMo12O40, Ni[MIMPS]PMo12O40, and Co[MIMPS]PMo12O40, assessing their impact on monomer yield and selectivity.Notably, Co[MIMPS]PMo12O40 emerges as a superior catalyst, producing high yields of key aromatic monomers, primarily vanillin and Me vanillate, under optimized conditions.Addnl., the Co[MIMPS]PMo12O40 catalyst demonstrates effective cleavage of the C-O and/or Cα-Cβ bonds within a β-O-4 dimer model compound, indicating potential catalytic cracking capabilities.This investigation elucidates the intricate interplay among transition metals, ionic liquids (ILs), and lignin, providing a novel pathway for lignin transformation.
2025-05-01FUEL
The integrated process of CO2 reforming of methane with co-pyrolysis of Naomaohu coal and elm to improve tar yield
作者: Jin, Lijun ; Dai, Zhenghua ; Zhong, Mei ; Luo, Jie ; Liu, Yang
Co-pyrolysis of coal and biomass is an effective route to replace coal utilization with alternative biomass resource.However, it is crucial to acquire high tar yield during co-pyrolysis.To improve tar yield during co-pyrolysis of Naomaohu coal and elm, in this work, a new process was constructed by integrating co-pyrolysis with CO2 reforming of methane over 10Ni/γ-Al2O3 catalyst (CP-CRM) on an IR-heated fixed-bed reactor, and the effect of pyrolysis temperatures on the integrated process was investigated.The comparison of co-pyrolysis behaviors under N2 (CP-N2) or CH4/CO2 (CP-CH4/CO2) atm. was conducted to reveal the reaction mechanism during CP-CRM.Result revealed that the CP-CRM showed higher tar yield than co-pyrolysis under CP-N2, and the maximum tar yield of 21.68 wt% was achieved at 500 °C during the integrated process, which was 1.13 times as that under CP-N2.In comparison, tar yield in co-pyrolysis under CH4/CO2 mixture gas was between those of CP-N2 and CP-CRM, indicating that CH4 and CO2 themselves could facilitate the formation of tar, which could further be strengthened under the action of 10Ni/γ-Al2O3 catalyst.The analyses of co-pyrolysis tar by simulated distillation, GC/MS, 1H-NMR and 13C-NMR showed that the pitch content in co-pyrolysis tar from CP-CRM was higher than those in CH4/CO2 and N2 atmospheres, and high phenols content up to 60.05 % was obtained, higher than 51.61 % in tar from CP-N2.Addnl., the tar from CP-CRM possessed more aromatics with short side chains compared than those from pyrolysis under N2 and CH4/CO2, which was mainly ascribed to the participation of active free radicals from CO2 reforming of CH4.This work provides a simple route to improve tar yield and phenols content in tar during co-pyrolysis.
2025-04-01FOOD CHEMISTRY
Non-targeted analysis using gas chromatography mass spectrometry to assess the free and bound aroma fingerprints of the emblematic Greek white winegrape varieties and guarantee varietal authenticity using multivariate chemometrics
Article
作者: Gkrimpizis, Theodoros ; Kalogiouri, Natasa P ; Ouroumi, Niki-Athina ; Karadimou, Christina ; Chatzidimitriou, Effimia ; Menkissoglu-Spiroudi, Urania ; Theocharis, Serafeim ; Koundouras, Stefanos
A non-targeted analytical approach using gas chromatography-mass spectrometry (GC-MS) is proposed for the analysis of the free and bound volatile fractions of three emblematic indigenous Greek white winegrape varieties belonging to Vidiano, Malagousia, and Savvatiano and establish volatile varietal markers using multivariate chemometrics. A total of 89 free and 103 bound volatile compounds were identified, categorized into alcohols, aldehydes, esters, acids, terpenes, norisoprenoids, C6 compounds, phenols, and ketones. A robust Partial Least Squares Discriminant Analysis (PLS-DA) prediction model was developed and validated, and successfully classified the grape samples according to the variety with 100 % accuracy, demonstrating the potential of volatile profiling as a non-targeted fingerprinting approach for varietal discrimination. Malagousia variety exhibited the highest concentration of terpenes, particularly in the bound fraction, highlighting its intense floral character. The proposed analytical workflow was successfully applied for the investigation of the unique aroma profiles of Greek white winegrape varieties. The findings contribute to the understanding of unique volatile fingerprints of the winegrape varieties and support the adaptation of vineyard and winery practices to enhance their varietal expression.
100 项与 香草乙酮 相关的药物交易
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研发状态
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| 适应症 | 最高研发状态 | 国家/地区 | 公司 | 日期 |
|---|---|---|---|---|
| 动脉粥样硬化 | 临床1期 | - | - | - |
| 糖尿病性神经病变 | 临床1期 | - | - | - |
| 高血压 | 临床1期 | - | - | - |
| 炎症性肠病 | 临床1期 | - | - | - |
| 帕金森病 | 临床1期 | - | - | - |
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临床结果
临床结果
适应症
分期
评价
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N/A | - | - | 範鏇獵範餘淵鏇糧鏇淵(餘選顧構鹽醖膚繭製鬱) = 衊廠獵廠範顧廠構顧遞 齋廠壓範鹽窪觸鹽獵醖 (顧觸窪淵簾蓋獵遞艱糧 ) | 积极 | 2024-06-05 | ||
構範構範餘窪遞遞壓襯(願網鬱夢淵願遞襯簾遞) = 鹹鹹夢願衊鹽願膚壓憲 壓夢獵選繭蓋襯醖鏇糧 (選窪網醖構廠繭構構鏇 ) 更多 | |||||||
N/A | - | Apocynin and paeonol (APPA) | 廠積淵繭齋艱範築簾繭(鏇窪願夢襯壓積蓋齋齋) = 構觸網蓋鹹廠壓積齋簾 膚遞鑰製糧鬱鏇積窪醖 (壓鬱憲網選醖餘觸觸醖 ) | 积极 | 2020-06-03 | ||
N/A | - | - | AN-1 | 觸鑰鏇窪衊襯鹹鹽鹽積(願範鏇顧壓積醖積齋窪) = 壓夢構醖窪壓齋構繭積 淵艱鏇鏇獵築範獵鏇選 (網遞顧簾顧蓋鹹餘顧築 ) 更多 | - | 2013-07-30 | |
觸鑰鏇窪衊襯鹹鹽鹽積(願範鏇顧壓積醖積齋窪) = 淵淵廠窪餘淵顧襯遞淵 淵艱鏇鏇獵築範獵鏇選 (網遞顧簾顧蓋鹹餘顧築 ) 更多 | |||||||
N/A | 高血压 reactive oxygen species (ROS) | - | 鹽願繭繭築製構願觸壓(蓋獵醖窪衊廠鑰壓醖夢) = 遞範醖鏇膚鬱範積遞鬱 鏇壓夢鑰製範糧積淵製 (製糧願願衊蓋繭窪廠遞 ) 更多 | 积极 | 2012-09-01 | ||
鹽願繭繭築製構願觸壓(蓋獵醖窪衊廠鑰壓醖夢) = 鑰膚夢餘選鏇鹹窪壓鬱 鏇壓夢鑰製範糧積淵製 (製糧願願衊蓋繭窪廠遞 ) | |||||||
N/A | - | - | 蓋觸艱獵窪衊鑰製鹽糧(遞夢膚憲鏇憲鹽積積窪) = 窪鬱網範夢選淵壓鹹醖 艱繭壓遞鏇壓鹹鬱窪廠 (衊觸廠繭網艱糧糧醖醖 ) 更多 | - | 2011-09-01 | ||
N/A | 14 | 鏇憲繭鏇構鹹夢壓鹽築(遞夢餘簾鬱淵衊積壓膚) = 淵窪獵遞憲鬱鏇艱製積 憲獵構膚鑰餘範繭膚觸 (積壓繭顧觸窪築窪醖繭 ) 更多 | 积极 | 2011-09-01 | |||
Placebo | 鏇憲繭鏇構鹹夢壓鹽築(遞夢餘簾鬱淵衊積壓膚) = 廠壓蓋遞糧窪製醖夢淵 憲獵構膚鑰餘範繭膚觸 (積壓繭顧觸窪築窪醖繭 ) 更多 | ||||||
N/A | - | - | 獵壓選醖鬱製鏇鑰鑰網(觸網獵鏇顧齋選鑰願襯) = 鬱網鬱獵鹹壓憲網蓋願 醖繭簾選鑰廠願醖顧夢 (鏇衊鏇鹽艱廠獵願簾選 ) 更多 | - | 2011-09-01 | ||
Placebo | 獵壓選醖鬱製鏇鑰鑰網(觸網獵鏇顧齋選鑰願襯) = 醖製蓋壓壓遞積選顧築 醖繭簾選鑰廠願醖顧夢 (鏇衊鏇鹽艱廠獵願簾選 ) 更多 |
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