Human anti-tetanus immunoglobulin(CSL Behring LLC)(Human anti-tetanus immunoglobulin(CSL Behring LLC)) - 药物靶点：Tetanus toxin_在研适应症：破伤风_专利_临床

概要

基本信息

药物类型

免疫球蛋白

别名

Tetagam、テタガム

靶点

Tetanus toxin

作用方式

抑制剂

作用机制

破伤风毒素抑制剂

治疗领域

感染其他疾病

在研适应症

破伤风

非在研适应症-

原研机构

CSL Behring LLC

在研机构

CSL Behring (Australia) Pty Ltd.

CSL Behring LLC

非在研机构-

最高研发阶段批准上市

首次获批日期

澳大利亚 (1991-11-04),

破伤风

最高研发阶段(中国)-

特殊审评-

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关联

100 项与 Human anti-tetanus immunoglobulin(CSL Behring LLC) 相关的临床结果

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100 项与 Human anti-tetanus immunoglobulin(CSL Behring LLC) 相关的转化医学

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100 项与 Human anti-tetanus immunoglobulin(CSL Behring LLC) 相关的专利（医药）

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1

项与 Human anti-tetanus immunoglobulin(CSL Behring LLC) 相关的文献（医药）

2006-11-01·Der Unfallchirurg4区 · 医学

Tetanusprophylaxe in der Notaufnahme

4区 · 医学

Article

作者: C. Krettek ; M. Frink ; C. W. Müller ; S. Ziesing

While tetanus is a rare disease in industrialized countries, this infectious disease is still responsible for up to 1,000,000 deaths per year in the developing world. In Germany, the introduction of a country-wide vaccination program (STIKO) has led to a decrease in the frequency of tetanus infection from 115 cases per year in the 1960s to fewer than 15 cases per year in the years from 1990 to 2000. In spite of all the treatment now available, tetanus infection still has a lethal outcome in up to 40% of cases. The Robert-Koch Institute recommends active or passive vaccination depending on the wound classification and the patient's current vaccination status. Since when patients have multiple trauma the emphasis while they are being treated for shock is on stabilisation and diagnosis, there is a real risk of underestimating the size and the level of contamination of existing wounds. Since it is not possible to ascertain the patient's vaccination status in most cases, we recommend simultaneous immunization of polytraumatized patients with skin lesions using Tetanol-Tetagam early in the course of the diagnostic procedures while the patients are still in the emergency room.

100 项与 Human anti-tetanus immunoglobulin(CSL Behring LLC) 相关的药物交易

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