In this paper, the solubility of menadiol diacetate in nine alcs. (methanol, ethanol, n-propanol, i-propanol, n-butanol, i-butanol, n-amyl alc., i-amyl alc., and cyclohexanol) and five n-alkyl acetates (Me acetate, Et acetate, Pr acetate, Bu acetate, and amyl acetate) was exptl. measured with the aid of a laser dynamic device at temperatures from 283.15 to 323.15 K.The solubility of menadiol diacetate as a function of temperature was regressed in terms of three semiempirical solubility models (Apelblat, van't Hoff, and λh), two activity coefficient solubility models (Wilson and NRTL), and the Jouyban model.The thermodn. mixing properties (mixing Gibbs energy, entropy, and enthalpy) of the solutions were estimated in terms of the measured solubility data and the regressed parameters of the Wilson model.