1986-01-01·Archivum immunologiae et therapiae experimentalis
Antitumor effect of selected daunorubicin derivatives in mice with P 388 leukemia.
Article
作者: Radzikowski, C ; Kuśnierczyk, H ; Rak, J
Antitumor activity of four modified on amino sugar moiety derivatives of daunorubicin was compared with activity of two commercial preparations of the parental drug in tests against P 388 leukemia in mice. Tested analogs appeared to be similarly effective as the reference drugs, but two of them, DR-2 and DR-19, were found to be significantly less potent.