A Study to Evaluate the Safety and Efficacy of Chlorthalidone in Combination With Amiloride as a Treatment for Elderly Patients With Arterial Hypertension

The purpose of this study is to assess the efficacy and safety of Chlorthalidone 25 mg + amiloride hydrochloride 5 mg association in the treatment of elderly patients with arterial hypertension.

开始日期2011-08-01

申办/合作机构

Eurofarma Laboratórios SA

100 项与氯噻酮/盐酸可乐定相关的临床结果

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100 项与氯噻酮/盐酸可乐定相关的转化医学

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100 项与氯噻酮/盐酸可乐定相关的专利（医药）

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项与氯噻酮/盐酸可乐定相关的文献（医药）

1980-11-01·Clinical Pharmacology and Therapeutics2区 · 医学

Clonidine-chlorthalidone combination once and twice daily in essential hypertension

2区 · 医学

Article

作者: Robert J Noveck ; Adesh K Jain ; F Gilbert McMahon ; Jerome R Ryan

The antihypertensive effects of a clonidine-chlorthalidone combination (Combipres) as a single daily dose at bedtime and the same amount in twice-daily doses were compared in an open-label, crossover study in 14 patients. An analysis of the blood pressure and pulse data in nine patients who completed the study revealed no statistically significant differences between the two regimens, and no difference in the incidence of side effects was noted.

1980-04-01·The Journal of Clinical Pharmacology3区 · 医学

Blood Pressure Response to a Single Daily Dose of a Clonidine—Chlorthalidone Combination

3区 · 医学

Article

作者: J. Caulie Gunnells ; Steven H. Grossman

A single evening dose of a clonidine-chlorthalidone combination (Combipres) was compared with the usual twice-daily schedule in 11 patients with essential hypertension. No significant difference was found between the blood pressures recorded on the two regimens or between morning and afternoon pressures on the once-daily schedule. Only one patient did not maintain adequate blood pressure control. We suggest that some patients with essential hypertension can be adequately treated with a single daily dose of a combination of clonidine and chlorthalidone.

1975-09-12·The Medical letter on drugs and therapeutics4区 · 医学

Combipres for hypertension.

4区 · 医学

Article

100 项与氯噻酮/盐酸可乐定相关的药物交易

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