Article
作者: Harrison, David ; Bock, Mark G. ; Gabel, Christopher A. ; Digby, Zsofia ; Watt, Alan P. ; Billinton, Andy ; Smolak, Pamela ; Thornton, Peter ; Wescott, Heather ; Clarke, Nicholas P. ; Scanlon, Jane ; Lindsay, Nicola ; Reader, Valérie
NT-0527 is a potent, specific and brain penetrant NLRP3 inflammasome inhibitor with oral bioavailability and efficacy in an
in vivo
model of inflammation.