Yttrium Y 90 monoclonal antibody Lym-1(University of California)(Yttrium Y 90 monoclonal antibody Lym-1(University of California))

概要

基本信息

药物类型

抗体偶联核素、治疗用放射药物

别名

90Y-DOTA-Peptide-Lym-1

靶点-

作用方式-

作用机制-

治疗领域

肿瘤免疫系统疾病血液及淋巴系统疾病

在研适应症-

非在研适应症

难治性非霍奇金淋巴瘤

原研机构

University of California, Davis

在研机构-

非在研机构

University of California, Davis

权益机构-

最高研发阶段无进展临床1期

首次获批日期-

最高研发阶段(中国)-

特殊审评-

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结构/序列

使用我们的ADC技术数据为新药研发加速。

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关联

2

项与 Yttrium Y 90 monoclonal antibody Lym-1(University of California) 相关的临床试验

NCT00009776

/ Unknown status临床1期IIT

Combined Modality Radioimmunotherapy For Non-Hodgkin's Lymphoma With Three Cycles Of 90Y-DOTA-peptide-Lym-1, Paclitaxel and Cyclosporin A

RATIONALE: Monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. Combining monoclonal antibody therapy with cyclosporine and paclitaxel may be an effective treatment for non-Hodgkin's lymphoma.
PURPOSE: Phase I trial to study the effectiveness of radiolabeled monoclonal antibody therapy combined with paclitaxel and cyclosporine in treating patients who have recurrent or refractory non-Hodgkin's lymphoma.

开始日期2001-03-01

申办/合作机构

University of California, Davis

NCT00008021

/ Unknown status临床1期IIT

A Phase I Study of 90Y-DOTA-Peptide-Lym-1 With Peripheral Blood Stem Cell Support, Paclitaxel And Cyclosporin A In Patients With Non-Hodgkin's Lymphoma

RATIONALE: Monoclonal antibodies can locate cancer cells and either kill them or deliver tumor-killing substances to them without harming normal cells. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Peripheral stem cell transplantation may allow doctors to give higher doses of chemotherapy and kill more cancer cells.
PURPOSE: Phase I trial to study the effectiveness of monoclonal antibody therapy, cyclosporine, and paclitaxel followed by peripheral stem cell transplantation in treating patients who have refractory non-Hodgkin's lymphoma.

开始日期2001-02-01

申办/合作机构

University of California, Davis

100 项与 Yttrium Y 90 monoclonal antibody Lym-1(University of California) 相关的临床结果

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100 项与 Yttrium Y 90 monoclonal antibody Lym-1(University of California) 相关的转化医学

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100 项与 Yttrium Y 90 monoclonal antibody Lym-1(University of California) 相关的专利（医药）

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100 项与 Yttrium Y 90 monoclonal antibody Lym-1(University of California) 相关的药物交易

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