Comparing Nail versus Locking Plate in displaced three-part proximal humerus fractures; A multi-centre randomized controlled trial (Otago PHINZ trial) investigating the effect on function post-operatively. .

开始日期2025-06-02

申办/合作机构

Health Research Council of New Zealand

ACTRN12624000479505 / Not yet recruitingN/AIIT

Investigating the effects of Mau rakau exercises (mahi a tinana) among people (tangata) 55 years and over with shoulder osteoarthritis.

开始日期2024-11-01

申办/合作机构

Health Research Council of New Zealand

[+1]

NCT06402786 / RecruitingN/AIIT

Wireless HOME Monitoring of Intracranial (BRAIN) PRESSURE

Patients with hydrocephalus have an abnormal build-up of fluid around the brain and need a tube surgically implanted to drain that fluid. Patients and their caregivers live with the constant fear that the tube will block. Warning symptoms include irritability, headaches and vomiting. Unfortunately, there is no way of telling when fluid build-up is causing a rise in brain pressure and potentially impeding blood flow to the brain (life threatening) except for a brain scan in hospital and possibly hospitalisation.
The investigators want to improve the lives of patients with hydrocephalus. They have developed a tool for parents and caregivers to monitor the pressure in the brain remotely via a sensor placed alongside the drainage tube. The device has been shown to be safe and to give reliable brain pressure readings using a large animal model (sheep). This study is a first-in-human safety study to show it is safe for patient use.

开始日期2024-05-27

申办/合作机构

Auckland University

[+3]

100 项与 Health Research Council of New Zealand 相关的临床结果

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0 项与 Health Research Council of New Zealand 相关的专利（医药）

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项与 Health Research Council of New Zealand 相关的文献（医药）

2021-04-10·Disability and Rehabilitation2区 · 医学

Understanding the therapeutic alliance in stroke rehabilitation

2区 · 医学

Article

作者: Bishop, Megan ; Kayes, Nicola ; McPherson, Kathryn

PURPOSEThe quality of the therapeutic alliance between a client and their clinician is thought to play an important role in healthcare but there is limited research about this concept in stroke rehabilitation. This study explored the core components of a therapeutic alliance and the factors perceived to impact on its development in a stroke rehabilitation unit.METHODSInterpretive description methodology was used to gather and synthesise participants' experiences of their therapeutic relationships. Ten individual client interviews and one clinician focus group were conducted. Data was were analysed using conventional content analysis.RESULTSA therapeutic alliance appeared to consist of three overlapping core components: a personal connection, a professional collaboration, and family collaboration. Clients valued these components to different degrees and priorities could change over time. Alliance breakdowns were perceived to stem from a clinician's incorrect assumptions about their client's relationship preferences or lack of responsiveness to their needs. Recovery of the alliance seemed to depend on the strength of the pre-existing relationship and steps taken to repair it.CONCLUSIONSEstablishing and maintaining a therapeutic alliance appears to be an individualised and complex process. A clinician's ability to use their personal attributes therapeutically, and professional skills flexibly, appeared integral to relationship quality.IMPLICATIONS FOR REHABILITATIONDeveloping therapeutic relationships requires a person-centred and sometimes family/whānau-centred approach.The judicious use of self-disclosure may achieve emotional proximity and yet maintain professional boundaries.Maintaining relationship health requires a proactive approach to detect and manage relationship disruptions.

2020-12-01·International Journal of Stroke2区 · 医学

Taking Charge after Stroke: A randomized controlled trial of a person-centered, self-directed rehabilitation intervention

2区 · 医学

Article

作者: Harwood, Matire ; Gommans, John ; McPherson, Kathryn ; Hanger, Carl ; Riley, Judith ; McRae, Anna ; Thomson, Tom ; Green, Geoff ; Ranta, Annemarei ; McNaughton, Harry ; Fu, Vivian ; Taylor, William ; Weatherall, Mark

Background and purpose “Take Charge” is a novel, community-based self-directed rehabilitation intervention which helps a person with stroke take charge of their own recovery. In a previous randomized controlled trial, a single Take Charge session improved independence and health-related quality of life 12 months following stroke in Māori and Pacific New Zealanders. We tested the same intervention in three doses (zero, one, or two sessions) in a larger study and in a broader non-Māori and non-Pacific population with stroke. We aimed to confirm whether the Take Charge intervention improved quality of life at 12 months after stroke in a different population and whether two sessions were more effective than one. Methods We randomized 400 people within 16 weeks of acute stroke who had been discharged to institution-free community living at seven centers in New Zealand to a single Take Charge session (TC1, n = 132), two Take Charge sessions six weeks apart (TC2, n = 138), or a control intervention (n = 130). Take Charge is a “talking therapy” that encourages a sense of purpose, autonomy, mastery, and connectedness with others. The primary outcome was the Physical Component Summary score of the Short Form 36 at 12 months following stroke comparing any Take Charge intervention to control. Results Of the 400 people randomized (mean age 72.2 years, 58.5% male), 10 died and two withdrew from the study. The remaining 388 (97%) people were followed up at 12 months after stroke. Twelve months following stroke, participants in either of the TC groups (i.e. TC1 + TC2) scored 2.9 (95% confidence intervals (CI) 0.95 to 4.9, p = 0.004) points higher (better) than control on the Short Form 36 Physical Component Summary. This difference remained significant when adjusted for pre-specified baseline variables. There was a dose effect with Short Form 36 Physical Component Summary scores increasing by 1.9 points (95% CI 0.8 to 3.1, p < 0.001) for each extra Take Charge session received. Exposure to the Take Charge intervention was associated with reduced odds of being dependent (modified Rankin Scale 3 to 5) at 12 months (TC1 + TC2 12% versus control 19.5%, odds ratio 0.55, 95% CI 0.31 to 0.99, p = 0.045). Conclusions Confirming the previous randomized controlled trial outcome, Take Charge—a low-cost, person-centered, self-directed rehabilitation intervention after stroke—improved health-related quality of life and independence. Clinical trial registration-URL http://www.anzctr.org.au . Unique identifier: ACTRN12615001163594

2020-12-01·Research Integrity and Peer Review

The acceptability of using a lottery to allocate research funding: a survey of applicants

Article

作者: Pomeroy, Lucy ; Liu, Mengyao ; Choy, Vernon ; Clarke, Philip ; Blakely, Tony ; Barnett, Adrian

AbstractBackgroundThe Health Research Council of New Zealand is the first major government funding agency to use a lottery to allocate research funding for their Explorer Grant scheme. This is a somewhat controversial approach because, despite the documented problems of peer review, many researchers believe that funding should be allocated solely using peer review, and peer review is used almost ubiquitously by funding agencies around the world. Given the rarity of alternative funding schemes, there is interest in hearing from the first cohort of researchers to ever experience a lottery. Additionally, the Health Research Council of New Zealand wanted to hear from applicants about the acceptability of the randomisation process and anonymity of applicants.MethodsThis paper presents the results of a survey of Health Research Council applicants from 2013 to 2019. The survey asked about the acceptability of using a lottery and if the lottery meant researchers took a different approach to their application.ResultsThe overall response rate was 39% (126 of 325 invites), with 30% (76 of 251) from applicants in the years 2013 to 2018, and 68% (50 of 74) for those in the year 2019 who were not aware of the funding result. There was agreement that randomisation is an acceptable method for allocating Explorer Grant funds with 63% (n = 79) in favour and 25% (n = 32) against. There was less support for allocating funds randomly for other grant types with only 40% (n = 50) in favour and 37% (n = 46) against. Support for a lottery was higher amongst those that had won funding. Multiple respondents stated that they supported a lottery when ineligible applications had been excluded and outstanding applications funded, so that the remaining applications were truly equal. Most applicants reported that the lottery did not change the time they spent preparing their application.ConclusionsThe Health Research Council’s experience through the Explorer Grant scheme supports further uptake of a modified lottery.

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